Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PRSS2 rightarrow Polyclonal PRSS2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • amyloid beta peptide 1-40 (Abeta1-40) ELISA Kit
 • CA125 Cancer Antigen Cancer Marker
 • anti-Mullerian hormone (AMH) ELISA Kit
 • Podocalyxin (PCX) Antibody
 • Cluster of differentiation 8 (CD8) ELISA Kit
 • COL4alpha1 ELISA Kit
 • ICAM-1 (ICAM-1-CD54) ELISA Kit
 • Coagulation factor X III (FX III) ELISA Kit
 • Lamin-A (LMNA) Recombinant Protein
 • Trefoil Factor 2 (TFF2) Antibody
 • nicotinamide adenine dinucleotide (NADH) (NADH2) ELISA Kit
 • Sialic acid-binding Ig-like lectin 15 (SIGLEC15) Recombinant Protein
 • Root allergen protein (RAP) Recombinant Protein
 • serpin peptidase inhibitor, clade G (C1 inhibitor) , member ... ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PRSS2 antibody :: Rabbit anti-Human, Mouse PRSS2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9128655
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRSS2, Polyclonal Antibody

★Popular Item★
 Also Known As   

PRSS2 Polyclonal Antibody

 Product Gene Name   

anti-PRSS2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 MBS9128655 COA    COA PDF
 OMIM    601564
 3D Structure    ModBase 3D Structure for P07478
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    Affinity Purification
Section Bar
 Immunogen    Recombinant Protein
 Synonyms    TRY2; TRY8; TRYP2
 Immunogen    Recombinant protein of human PRSS2
Section Bar
 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-PRSS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-PRSS2 antibody

   This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
 Applications Tested/Suitable for anti-PRSS2 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-PRSS2 antibody    WB 1:500 - 1:2000
IHC 1:50 - 1:200
Section Bar
 Western Blot (WB) of anti-PRSS2 antibody    Western blot analysis of extracts of various cell lines, using PRSS2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-PRSS2 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PRSS2. It may not necessarily be applicable to this product.
 NCBI GI #    4506147
 NCBI GeneID    5645
 NCBI Accession #    NP_002761.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002770.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P07478 [Other Products]
 UniProt Related Accession #    P07478 [Other Products]
 Molecular Weight    26kDa
Table BarTOPTable Bar
 NCBI Official Full Name    trypsin-2 isoform 2 preproprotein
 NCBI Official Synonym Full Names    protease, serine, 2 (trypsin 2)
 NCBI Official Symbol    PRSS2 [Similar Products]
 NCBI Official Synonym Symbols   
TRY2; TRY8; TRYP2
[Similar Products]
 NCBI Protein Information    trypsin-2
 UniProt Protein Name    Trypsin-2
 UniProt Synonym Protein Names   
Anionic trypsinogen; Serine protease 2; Trypsin II
 Protein Family    Trypsin
 UniProt Gene Name    PRSS2 [Similar Products]
 UniProt Synonym Gene Names    TRY2; TRYP2 [Similar Products]
 UniProt Entry Name    TRY2_HUMAN
Section Bar
 NCBI Summary for PRSS2    This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]
Section Bar
 UniProt Comments for PRSS2    trypsin 2: In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family.

Protein type: Calcium-binding; Cell adhesion; EC 3.4.21.4; Secreted, signal peptide; Secreted; Extracellular matrix; Protease

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: protein binding; serine-type endopeptidase activity; calcium ion binding

Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; positive regulation of cell adhesion; digestion; innate immune response; proteolysis; positive regulation of cell growth

Disease: Pancreatitis, Hereditary
Table BarTOPTable Bar
 Research Articles on PRSS2    1. Serum trypsinogen-2 is associated with pancreatic cancer and pancreatitis.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-PRSS2 antibodyDiseases associated with anti-PRSS2 antibody
 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Alpha-defensins Pathway antibodies  Alpha-defensins Pathway Diagram
 Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies  Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Disease Name  Pubmed Publications
 Pancreatitis, Chronic Antibodies  >49 publications with PRSS2 and Pancreatitis, Chronic
 Fibrosis Antibodies  >27 publications with PRSS2 and Fibrosis
 Pancreatic Neoplasms Antibodies  >14 publications with PRSS2 and Pancreatic Neoplasms
 Adenocarcinoma Antibodies  >10 publications with PRSS2 and Adenocarcinoma
 Inflammation Antibodies  >8 publications with PRSS2 and Inflammation
 Respiratory Tract Diseases Antibodies  >7 publications with PRSS2 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >7 publications with PRSS2 and Lung Diseases
 Liver Neoplasms Antibodies  >2 publications with PRSS2 and Liver Neoplasms
 Diabetes Mellitus Antibodies  >2 publications with PRSS2 and Diabetes Mellitus
 Lung Injury Antibodies  >2 publications with PRSS2 and Lung Injury
Organs/Tissues associated with anti-PRSS2 antibody
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >34 publications with PRSS2 and Pancreas
 Intestine Antibodies  >4 publications with PRSS2 and Intestine
 Liver Antibodies  >4 publications with PRSS2 and Liver
 Lung Antibodies  >2 publications with PRSS2 and Lung
 Testis Antibodies  >1 publications with PRSS2 and Testis
 Prostate Antibodies  >1 publications with PRSS2 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions