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anti-PSCA antibody :: Rabbit anti-Human, Mouse PSCA Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2539386
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PSCA, Polyclonal Antibody

★Popular Item★
 Also Known As   

PSCA Polyclonal Antibody

 Product Synonym Names    PSCA; Prostate stem cell antigen
 Product Gene Name   

anti-PSCA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2539386 Technical Datasheet    Technical Datasheet PDF
 OMIM    602470
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
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 Immunogen    Synthesized peptide derived from the Internal region of human PSCA.
 Buffer    PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14201 / sc-14202
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PSCA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PSCA antibody

   PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
 Product Categories/Family for anti-PSCA antibody    Stem cells
 Applications Tested/Suitable for anti-PSCA antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-PSCA antibody    WB: 1:500-1:2000, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-PSCA antibody    Western Blot analysis of various cells using PSCA Polyclonal Antibody at dilution of 1:1000.
anti-PSCA antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for PSCA. It may not necessarily be applicable to this product.
 NCBI GI #    289547757
 NCBI GeneID    8000
 NCBI Accession #    NP_005663.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005672.4 [Other Products]
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 UniProt Secondary Accession #    Q6UW92 [Other Products]
 UniProt Related Accession #    O43653 [Other Products]
 Molecular Weight    Calculated MW: 13kDa
Observed MW: 29kDa
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 NCBI Official Full Name    prostate stem cell antigen preproprotein
 NCBI Official Synonym Full Names    prostate stem cell antigen
 NCBI Official Symbol    PSCA [Similar Products]
 NCBI Official Synonym Symbols   
PRO232
[Similar Products]
 NCBI Protein Information    prostate stem cell antigen
 UniProt Protein Name    Prostate stem cell antigen
 Protein Family    Prostate stem cell antigen
 UniProt Gene Name    PSCA [Similar Products]
 UniProt Entry Name    PSCA_HUMAN
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 NCBI Summary for PSCA    This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
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 UniProt Comments for PSCA    PSCA: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 8q24.2

Cellular Component: plasma membrane
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 Research Articles on PSCA    1. These results suggest that PSCA gene variation has a potential effect on its expression and gastric adenocarcinoma risk in the Northwest Chinese population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PSCA antibodyOrgans/Tissues associated with anti-PSCA antibody
 Reference Product  PubMed Publications
 NKX3-1 antibody  >7 publications with PSCA and NKX3-1
 ERBB2 antibody  >4 publications with PSCA and ERBB2
 S100P antibody  >3 publications with PSCA and S100P
 STEAP1 antibody  >3 publications with PSCA and STEAP1
 YY1 antibody  >2 publications with PSCA and YY1
 OR51E2 antibody  >1 publications with PSCA and OR51E2
 KLK4 antibody  >1 publications with PSCA and KLK4
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >261 publications with PSCA and Prostate
 Stomach Antibodies  >49 publications with PSCA and Stomach
 Bladder Antibodies  >47 publications with PSCA and Bladder
 Bone Antibodies  >21 publications with PSCA and Bone
 Pancreas Antibodies  >16 publications with PSCA and Pancreas
 Brain Antibodies  >8 publications with PSCA and Brain
 Kidney Antibodies  >7 publications with PSCA and Kidney
 Lung Antibodies  >6 publications with PSCA and Lung
 Liver Antibodies  >6 publications with PSCA and Liver
 Eye Antibodies  >2 publications with PSCA and Eye
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