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anti-PSG4 antibody :: Rabbit anti-Human PSG4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9207025
Western Blot (WB)
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PSG4, Polyclonal Antibody

 Also Known As   

PSG4 Antibody (N-term)

 Product Synonym Names    Pregnancy-specific beta-1-glycoprotein 4; PS-beta-G-4; PSBG-4; Pregnancy-specific glycoprotein 4; Pregnancy-specific beta-1-glycoprotein 9; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9; PSG4; CGM4; PSG9
 Product Gene Name   

anti-PSG4 antibody

[Similar Products]
 Antibody/Peptide Pairs    PSG4 peptide (MBS9223957) is used for blocking the activity of PSG4 antibody (MBS9207025)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    73-100
 OMIM    176393
 3D Structure    ModBase 3D Structure for Q00888
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4.
 Purity/Purification    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
 Concentration    Vial Concentration: 0.5 (lot specific)
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 Antigen Type    Synthetic Peptide
 Antigen Source    HUMAN
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-PSG4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PSG4 antibody

   The human pregnancy-specific glycoproteins (PSGs) are a
family of proteins that are synthesized in large amounts by
placental trophoblasts and released into the maternal circulation
during pregnancy. Molecular cloning and analysis of several PSG
genes has indicated that the PSGs form a subgroup of the
carcinoembryonic antigen (CEA) gene family, which belongs to the
immunoglobulin superfamily of genes. Members of the CEA family
consist of a single N domain, with structural similarity to the
immunoglobulin variable domains, followed by a variable number of
immunoglobulin constant-like A and/or B domains. Most PSGs have an
arg-gly-asp (RGD) motif, which has been shown to function as an
adhesion recognition signal for several integrins, in the
N-terminal domain (summary by Teglund et al., 1994 [PubMed
7851896]). For additional general information about the PSG gene
family, see PSG1 (MIM 176390).
 Product Categories/Family for anti-PSG4 antibody    Developmental Biology
 Applications Tested/Suitable for anti-PSG4 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-PSG4 antibody    WB~~1:1000
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 Western Blot (WB) of anti-PSG4 antibody    PSG4 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PSG4 antibody detected the PSG4 protein (arrow).
anti-PSG4 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for PSG4. It may not necessarily be applicable to this product.
 NCBI GI #    42560235
 NCBI GeneID    5672
 NCBI Accession #    NP_002771.2 [Other Products]
 NCBI Related Accession #    NP_998798.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002780.4 [Other Products]
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 UniProt Primary Accession #    Q00888 [Other Products]
 UniProt Secondary Accession #    Q13047; Q13048; Q15234; Q15240; Q9UQ76; E7EX79 [Other Products]
 UniProt Related Accession #    Q00888 [Other Products]
 Molecular Weight    47113
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 NCBI Official Full Name    pregnancy-specific beta-1-glycoprotein 4 isoform 1
 NCBI Official Synonym Full Names    pregnancy specific beta-1-glycoprotein 4
 NCBI Official Symbol    PSG4 [Similar Products]
 NCBI Official Synonym Symbols   
PSG9
[Similar Products]
 NCBI Protein Information    pregnancy-specific beta-1-glycoprotein 4
 UniProt Protein Name    Pregnancy-specific beta-1-glycoprotein 4
 UniProt Synonym Protein Names   
Pregnancy-specific beta-1-glycoprotein 9; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9
 Protein Family    Pregnancy-specific beta-1-glycoprotein
 UniProt Gene Name    PSG4 [Similar Products]
 UniProt Synonym Gene Names    CGM4; PSG9; PS-beta-G-4; PSBG-4; Pregnancy-specific glycoprotein 4; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9 [Similar Products]
 UniProt Entry Name    PSG4_HUMAN
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 NCBI Summary for PSG4    The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
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 UniProt Comments for PSG4    PSG4: Belongs to the immunoglobulin superfamily. CEA family. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.2

Biological Process: female pregnancy
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Product References and Citations for anti-PSG4 antibody

   Kimoto, Y. Mol. Gen. Genet. 258(3):233-239(1998)
Teglund, S., et al. Biochem. Biophys. Res. Commun. 211(2):656-664(1995)
Teglund, S., et al. Genomics 23(3):669-684(1994)
Olsen, A., et al. Genomics 23(3):659-668(1994)
Chan, W.Y., et al. Mol. Cell. Biochem. 106(2):161-170(1991)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-PSG4 antibodyOrgans/Tissues associated with anti-PSG4 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with PSG4 and Carcinoma
 Adenocarcinoma Antibodies  >1 publications with PSG4 and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >4 publications with PSG4 and Placenta
 Liver Antibodies  >2 publications with PSG4 and Liver
 Embryonic Tissue Antibodies  >1 publications with PSG4 and Embryonic Tissue
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