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anti-PVALB antibody :: Goat Parvalbumin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420829
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Parvalbumin (PVALB), Polyclonal Antibody

 Also Known As   

Goat anti-Parvalbumin Antibody

 Product Synonym Names    parvalbumin; HGNC: 9704; PVALB; D22S749; parvalbumin alpha; MGC116759; parvalbumin antibody; HGNC: 9704 antibody; PVALB antibody; D22S749 antibody; parvalbumin alpha antibody; MGC116759 antibody; Parvalbumin; Parvalbumin
 Product Gene Name   

anti-PVALB antibody

[Similar Products]
 Antibody/Peptide Pairs    Parvalbumin peptide (MBS426648) is used for blocking the activity of Parvalbumin antibody (MBS420829)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    GVDEFSTLVA ES
 OMIM    168890
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human, Rat; Expected from sequence similarity: Human, Rat
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-GVDEFSTLVAES, from the C Terminus of the protein sequence according to NP_002845.1.
 Epitope    C Terminus
 Note    Reported variants represent identical protein: NP_002845.1, NP_001302461.1
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-PVALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PVALB antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-PVALB antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
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 Western Blot (WB) of anti-PVALB antibody    (0.1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-PVALB antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-PVALB antibody    (0.15ug/ml) staining of adenovirus-mediated gene transfer in rat heart cells 1) Untransfected, 2) transient transfection with Human PVALB.3) Untransfected rat skeletal muscle. Primary incubation was 1 hour. Detected by chemiluminescence.
anti-PVALB antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for PVALB. It may not necessarily be applicable to this product.
 NCBI GI #    4506335
 NCBI GeneID    5816
 NCBI Accession #    NP_002845.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002854.2 [Other Products]
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 UniProt Secondary Accession #    P78378; Q4VB78; Q5R3Q9; B2R4H7 [Other Products]
 UniProt Related Accession #    P20472 [Other Products]
 Molecular Weight    12,059 Da
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 NCBI Official Full Name    parvalbumin alpha
 NCBI Official Synonym Full Names    parvalbumin
 NCBI Official Symbol    PVALB [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    parvalbumin alpha
 UniProt Protein Name    Parvalbumin alpha
 Protein Family    Parvalbumin
 UniProt Gene Name    PVALB [Similar Products]
 UniProt Entry Name    PRVA_HUMAN
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 NCBI Summary for PVALB    The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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 UniProt Comments for PVALB    PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cell soma; cytosol; nucleus; protein complex; terminal button

Molecular Function: calcium ion binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: cytosolic calcium ion homeostasis
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 Research Articles on PVALB    1. Increased numbers of PVALB neurons and fiber labeling in focal cortical dysplasia compared to nondysplastic epileptic temporal neocortex and postmortem controls may be related to cortical malformation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-PVALB antibodyOrgans/Tissues associated with anti-PVALB antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with PVALB and Nervous System Diseases
 Prenatal Exposure Delayed Effects Antibodies  >4 publications with PVALB and Prenatal Exposure Delayed Effects
 Schizophrenia Antibodies  >4 publications with PVALB and Schizophrenia
 Kidney Diseases Antibodies  >3 publications with PVALB and Kidney Diseases
 Adenoma, Oxyphilic Antibodies  >2 publications with PVALB and Adenoma, Oxyphilic
 Carcinoma, Renal Cell Antibodies  >2 publications with PVALB and Carcinoma, Renal Cell
 Brain Diseases Antibodies  >2 publications with PVALB and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with PVALB and Disease Models, Animal
 Atrophy Antibodies  >2 publications with PVALB and Atrophy
 Poisoning Antibodies  >2 publications with PVALB and Poisoning
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with PVALB and Brain
 Thyroid Antibodies  >5 publications with PVALB and Thyroid
 Kidney Antibodies  >5 publications with PVALB and Kidney
 Eye Antibodies  >2 publications with PVALB and Eye
 Ovary Antibodies  >1 publications with PVALB and Ovary
 Mammary Gland Antibodies  >1 publications with PVALB and Mammary Gland
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