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anti-PYY antibody :: Rabbit Peptide YY Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS534660 anti-PYY antibody
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 Product Name   

Peptide YY (PYY), Polyclonal Antibody

 Also Known As   

Peptide YY antibody

 Product Synonym Names    Polyclonal Peptide YY; Anti-Peptide YY; PYY
 Product Gene Name   

anti-PYY antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600781
 3D Structure    ModBase 3D Structure for P10082
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 Clonality    Polyclonal
 Isotype    IgG1
 Host    Rabbit
 Species Reactivity    Cat, Human, Pig, Rat
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 Specificity    Porcine peptide YY
 Form/Format    Supplied as Neat serum with 0.1% NaN3.
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 Biological Significance    The intestinal peptide YY is related to the PP-family of peptides and occurs in glicentin cells in the gut. They are found in the rectum, colon, ileum, and to a lower extent in the duodenum and jejunum. PYY may occur in endocrine tumors of the pancreas and the rectum.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Immunogen    Peptide YY antibody was raised in rabbit using porcine PYY as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-PYY antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PYY antibody

   Rabbit polyclonal Peptide YY antibody
 Product Categories/Family for anti-PYY antibody    Nutrition & Metabolism
 Applications Tested/Suitable for anti-PYY antibody   

Immunohistochemistry (IHC) Formalin/Paraffin

 Application Notes for anti-PYY antibody    IHC-F: 1:50
IHC-P: 1:50
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NCBI/Uniprot data below describe general gene information for PYY. It may not necessarily be applicable to this product.
 NCBI GI #    409745
 NCBI GeneID    5697
 NCBI Accession #    AAA36433.1 [Other Products]
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 UniProt Primary Accession #    P10082 [Other Products]
 UniProt Secondary Accession #    Q5U5Q6; Q6FGH8 [Other Products]
 UniProt Related Accession #    P10082 [Other Products]
 Molecular Weight    10,360 Da [Similar Products]
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 NCBI Official Full Name    peptide YY
 NCBI Official Synonym Full Names    peptide YY
 NCBI Official Symbol    PYY [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    peptide YY
 UniProt Protein Name    Peptide YY
 UniProt Synonym Protein Names   
 Protein Family    Peptide
 UniProt Gene Name    PYY [Similar Products]
 UniProt Synonym Gene Names    PYY [Similar Products]
 UniProt Entry Name    PYY_HUMAN
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 NCBI Summary for PYY    The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]
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 UniProt Comments for PYY    PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: extracellular space; extracellular region

Molecular Function: neuropeptide hormone activity; protein binding; G-protein-coupled receptor binding; hormone activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell proliferation; cell-cell signaling; eating behavior; neuropeptide signaling pathway; digestion; regulation of appetite; feeding behavior; cytoskeleton organization and biogenesis; cell motility

Disease: Obesity
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 Research Articles on PYY    1. These results indicate that circulating PYY may have buffering effects during the early stages of smoking cessation while ghrelin may confer increased risk of smoking relapse.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PYY antibodyPathways associated with anti-PYY antibody
 Reference Product  PubMed Publications
 CCK antibody  >244 publications with PYY and CCK
 POMC antibody  >49 publications with PYY and POMC
 SST antibody  >7 publications with PYY and SST
 NPY2R antibody  >6 publications with PYY and NPY2R
 NPY1R antibody  >4 publications with PYY and NPY1R
 GAL antibody  >3 publications with PYY and GAL
 CCL28 antibody  >2 publications with PYY and CCL28
 NPY5R antibody  >1 publications with PYY and NPY5R
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with anti-PYY antibodyOrgans/Tissues associated with anti-PYY antibody
 Disease Name  Pubmed Publications
 Obesity Antibodies  >430 publications with PYY and Obesity
 Weight Loss Antibodies  >176 publications with PYY and Weight Loss
 Gastrointestinal Diseases Antibodies  >131 publications with PYY and Gastrointestinal Diseases
 Weight Gain Antibodies  >94 publications with PYY and Weight Gain
 Insulin Resistance Antibodies  >80 publications with PYY and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >64 publications with PYY and Diabetes Mellitus, Type 2
 Anorexia Antibodies  >63 publications with PYY and Anorexia
 Hyperinsulinism Antibodies  >52 publications with PYY and Hyperinsulinism
 Inflammation Antibodies  >47 publications with PYY and Inflammation
 Carcinoma Antibodies  >46 publications with PYY and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >511 publications with PYY and Intestine
 Brain Antibodies  >410 publications with PYY and Brain
 Kidney Antibodies  >63 publications with PYY and Kidney
 Testis Antibodies  >2 publications with PYY and Testis
 Uncharacterized Tissue Antibodies  >1 publications with PYY and Uncharacterized Tissue
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