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anti-POSTN antibody :: Rabbit anti-Mouse Periostin (POSTN) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2014105 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-POSTN antibody
Unit / Price
0.1 mg  /  $265 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Periostin (POSTN), Polyclonal Antibody

★Popular Item★
 Also Known As   

FITC-linked Antibody to Periostin (POSTN)

 Product Gene Name   

anti-POSTN antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Periostin (POSTN) (MBS2003789)
FITC Conjugated Antibody: Periostin (POSTN) (MBS2014105)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 13; NC_000013.10 (38136719..38172981, complement). Location: 13q13.3
 OMIM    608777
 3D Structure    ModBase 3D Structure for Q15063
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse
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 Purity/Purification    Antigen-specific Affinity Chromatography.
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Antibody labeling
 Label    FITC
 Traits    Liquid
 Immunogen    Recombinant POSTN (Ser500-Leu630) expressed in E.cali.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-POSTN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-POSTN antibody    FITC Antibody
 Applications Tested/Suitable for anti-POSTN antibody   

Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)

 Application Notes for anti-POSTN antibody    Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
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NCBI/Uniprot data below describe general gene information for POSTN. It may not necessarily be applicable to this product.
 NCBI GI #    209862907
 NCBI GeneID    10631
 NCBI Accession #    NP_006466.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006475.2 [Other Products]
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 UniProt Primary Accession #    Q15063 [Other Products]
 UniProt Secondary Accession #    Q15064; Q29XZ0; Q3KPJ5; Q5VSY5; Q8IZF9 [Other Products]
 UniProt Related Accession #    Q15063 [Other Products]
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 NCBI Official Full Name    periostin isoform 1
 NCBI Official Synonym Full Names    periostin, osteoblast specific factor
 NCBI Official Symbol    POSTN [Similar Products]
 NCBI Official Synonym Symbols   
PN; OSF2; OSF-2; PDLPOSTN; periostin
[Similar Products]
 NCBI Protein Information    periostin; periodontal ligament-specific periostin; osteoblast specific factor 2 (fasciclin I-like)
 UniProt Protein Name    Periostin
 UniProt Synonym Protein Names   
Osteoblast-specific factor 2
 Protein Family    Periostin
 UniProt Gene Name    POSTN [Similar Products]
 UniProt Synonym Gene Names    OSF2; PN; OSF-2 [Similar Products]
 UniProt Entry Name    POSTN_HUMAN
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 NCBI Summary for POSTN    This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
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 UniProt Comments for POSTN    POSTN: Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Motility/polarity/chemotaxis; Cell adhesion; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 13q13.3

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; trans-Golgi network

Molecular Function: heparin binding; protein binding; cell adhesion molecule binding

Biological Process: tissue development; extracellular matrix organization and biogenesis; regulation of Notch signaling pathway; cell adhesion; skeletal development
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 Research Articles on POSTN    1. under hypoxic conditions, POSTN regulates PHD2 expression and HIF-1alpha levels by modulating TGF-beta1 signaling, leading to decreased apoptosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-POSTN antibodyDiseases associated with anti-POSTN antibody
 Reference Product  PubMed Publications
 TGFB1 antibody  >27 publications with POSTN and TGFB1
 COL1A1 antibody  >7 publications with POSTN and COL1A1
 COL3A1 antibody  >6 publications with POSTN and COL3A1
 DCN antibody  >5 publications with POSTN and DCN
 FN1 antibody  >5 publications with POSTN and FN1
 COL1A2 antibody  >4 publications with POSTN and COL1A2
 CLCA1 antibody  >2 publications with POSTN and CLCA1
 SERPINB2 antibody  >2 publications with POSTN and SERPINB2
 COL5A2 antibody  >2 publications with POSTN and COL5A2
 LUM antibody  >2 publications with POSTN and LUM
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >123 publications with POSTN and Neoplasms
 Carcinoma Antibodies  >64 publications with POSTN and Carcinoma
 Fibrosis Antibodies  >47 publications with POSTN and Fibrosis
 Neoplasm Metastasis Antibodies  >34 publications with POSTN and Neoplasm Metastasis
 Inflammation Antibodies  >31 publications with POSTN and Inflammation
 Disease Models, Animal Antibodies  >31 publications with POSTN and Disease Models, Animal
 Adenocarcinoma Antibodies  >28 publications with POSTN and Adenocarcinoma
 Breast Neoplasms Antibodies  >21 publications with POSTN and Breast Neoplasms
 Myocardial Infarction Antibodies  >16 publications with POSTN and Myocardial Infarction
 Heart Failure Antibodies  >16 publications with POSTN and Heart Failure
Organs/Tissues associated with anti-POSTN antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >32 publications with POSTN and Embryonic Tissue
 Thyroid Antibodies  >4 publications with POSTN and Thyroid
 Pancreas Antibodies  >4 publications with POSTN and Pancreas
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