AAA67895.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,388 Da
NCBI Official Full Name
phenol sulfotransferase
NCBI Official Synonym Full Names
sulfotransferase family 1A member 1
NCBI Official Synonym Symbols
PST; STP; STP1; P-PST; ST1A1; ST1A3; TSPST1; HAST1/HAST2 [Similar Products]
NCBI Protein Information
sulfotransferase 1A1
UniProt Protein Name
Sulfotransferase 1A1
UniProt Synonym Protein Names
Aryl sulfotransferase 1; HAST1/HAST2; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; P-PST 1; ST1A3; Thermostable phenol sulfotransferase; Ts-PST
UniProt Synonym Gene Names
NCBI Summary for PST
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for PST
SULT1A1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N- hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.8.2.1; Energy Metabolism - sulfur; Transferase
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: cytosol
Molecular Function: aryl sulfotransferase activity; flavonol 3-sulfotransferase activity; protein binding; steroid sulfotransferase activity; sulfotransferase activity
Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine metabolic process; catecholamine metabolic process; estrogen metabolic process; ethanol catabolic process; flavonoid metabolic process; sulfation; xenobiotic metabolic process
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Pathways associated with anti-PST antibody
Diseases associated with anti-PST antibody
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