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anti-FUCA2 antibody :: Rabbit anti-Human Plasma alpha-L-fucosidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS719461
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Plasma alpha-L-fucosidase (FUCA2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Plasma alpha-L-fucosidase polyclonal Antibody

 Product Synonym Names    Alpha-L-fucoside fucohydrolase 2; FUCA2; PSEC0151; UNQ227/PRO260
 Product Gene Name   

anti-FUCA2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    136820
 3D Structure    ModBase 3D Structure for Q9BTY2
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Plasma alpha-L-fucosidase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130759
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FUCA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FUCA2 antibody

   Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
 Applications Tested/Suitable for anti-FUCA2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-FUCA2 antibody    All lanes: Plasma alpha-L-fucosidase antibody at 2ug/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55,20 kDa
Observed band size: 51 kDa

anti-FUCA2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-FUCA2 antibody    Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS719461 at dilution of 1:50
anti-FUCA2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for FUCA2. It may not necessarily be applicable to this product.
 NCBI GI #    40068512
 NCBI GeneID    2519
 NCBI Accession #    NP_114409.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_032020.4 [Other Products]
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 UniProt Primary Accession #    Q9BTY2 [Other Products]
 UniProt Secondary Accession #    Q7Z6V1; Q7Z6Y2; Q8NBK4; E9PEB6 [Other Products]
 UniProt Related Accession #    Q9BTY2 [Other Products]
 Molecular Weight    19,835 Da [Similar Products]
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 NCBI Official Full Name    plasma alpha-L-fucosidase
 NCBI Official Synonym Full Names    fucosidase, alpha-L- 2, plasma
 NCBI Official Symbol    FUCA2 [Similar Products]
 NCBI Official Synonym Symbols   
dJ20N2.5
[Similar Products]
 NCBI Protein Information    plasma alpha-L-fucosidase
 UniProt Protein Name    Plasma alpha-L-fucosidase
 UniProt Synonym Protein Names   
Alpha-L-fucoside fucohydrolase 2; Alpha-L-fucosidase 2
 Protein Family    Plasma alpha-L-fucosidase
 UniProt Gene Name    FUCA2 [Similar Products]
 UniProt Synonym Gene Names    Alpha-L-fucosidase 2 [Similar Products]
 UniProt Entry Name    FUCO2_HUMAN
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 NCBI Summary for FUCA2    This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]
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 UniProt Comments for FUCA2    FUCA2: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins. Belongs to the glycosyl hydrolase 29 family.

Protein type: Secreted, signal peptide; Hydrolase; EC 3.2.1.51; Secreted; Glycan Metabolism - other glycan degradation

Chromosomal Location of Human Ortholog: 6q24

Cellular Component: extracellular space

Molecular Function: alpha-L-fucosidase activity; protein binding

Biological Process: fucose metabolic process; glycoside catabolic process; response to bacterium
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 Research Articles on FUCA2    1. IL-13, IL-4 and IL-5 have no effect on the expression of FUCA1 and FUCA2, but its expression is upregulated by IFN-gamma, a Th1 cytokine.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-FUCA2 antibodyDiseases associated with anti-FUCA2 antibody
 Products by Pathway  Pathway Diagram
 Other Glycan Degradation Pathway antibodies  Other Glycan Degradation Pathway Diagram
 Other Glycan Degradation Pathway antibodies  Other Glycan Degradation Pathway Diagram
 Disease Name  Pubmed Publications
 Aneuploidy Antibodies  >1 publications with FUCA2 and Aneuploidy
 Abnormalities, Multiple Antibodies  >1 publications with FUCA2 and Abnormalities, Multiple
 Liver Diseases Antibodies  >1 publications with FUCA2 and Liver Diseases
 Inflammation Antibodies  >1 publications with FUCA2 and Inflammation
 Kidney Diseases Antibodies  >1 publications with FUCA2 and Kidney Diseases
Organs/Tissues associated with anti-FUCA2 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with FUCA2 and Blood
 Liver Antibodies  >1 publications with FUCA2 and Liver
 Stomach Antibodies  >1 publications with FUCA2 and Stomach
 Kidney Antibodies  >1 publications with FUCA2 and Kidney
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