Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PF4 rightarrow Polyclonal PF4  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • SSFA2 ELISA Kit
 • PSMA4 Antibody
 • TUBB ELISA Kit
 • butyrylcholinesterase (BCHE) ELISA Kit
 • ubc7 (ubiquitin Conjugating enzyme 7) Recombinant Protein
 • MSH6 Antibody
 • GON4L Antibody
 • Bcl2 Associated X Protein (Bax) ELISA Kit
 • CSTA ELISA Kit
 • D-Dimer (Fibrin Degradation Product) Antibody
 • Runt Related Transcription Factor 2 (RUNX2) ELISA Kit
 • Urease subunit alpha (ureC) Recombinant Protein
 • SP1-T739 Antibody
 • AAK1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PF4 antibody :: Rabbit Platelet Factor 4 (PF4) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2039119 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-PF4 antibody
Unit / Price
0.01 mg  /  $100 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $150 +1 FREE 8GB USB
0.1 mg  /  $195 +1 FREE 8GB USB
0.2 mg  /  $270 +1 FREE 8GB USB
1 mg  /  $635 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Platelet Factor 4 (PF4), Polyclonal Antibody

★Popular Item★
 Also Known As   

FITC-Linked Polyclonal Antibody to Platelet Factor 4 (PF4)

 Product Synonym Names    CXCL4; SCYB4; Chemokine C-X-C-Motif Ligand 4; Oncostatin-A; Iroplact
 Product Gene Name   

anti-PF4 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Platelet Factor 4 (PF4) (MBS2003720)
FITC Conjugated Antibody: Platelet Factor 4 (PF4) (MBS2039119)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    M25897 mRNA
 3D Structure    ModBase 3D Structure for P02776
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mus musculus (Mouse)
Section Bar
 Purity/Purification    Antigen-specific Affinity Chromatography.
 Form/Format    Supplied as solution form in 0.01M CBS, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    0.49mg/ml (lot specific)
Section Bar
 Source    Antibody labeling
 Label    FITC
 Traits    Liquid
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2003720
Section Bar
 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-PF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-PF4 antibody   

WB; IHC; ICC; IF.

 Application Notes for anti-PF4 antibody    Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PF4. It may not necessarily be applicable to this product.
 NCBI GI #    4505733
 NCBI GeneID    5196
 NCBI Accession #    NP_002610.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002619.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P02776 [Other Products]
 UniProt Secondary Accession #    Q53X61; Q9UC64; Q9UC65 [Other Products]
 UniProt Related Accession #    P02776 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    platelet factor 4
 NCBI Official Synonym Full Names    platelet factor 4
 NCBI Official Symbol    PF4 [Similar Products]
 NCBI Official Synonym Symbols   
PF-4; CXCL4; SCYB4
[Similar Products]
 NCBI Protein Information    platelet factor 4
 UniProt Protein Name    Platelet factor 4
 UniProt Synonym Protein Names   
C-X-C motif chemokine 4; Iroplact; Oncostatin-A
 Protein Family    Platelet factor
 UniProt Gene Name    PF4 [Similar Products]
 UniProt Synonym Gene Names    CXCL4; SCYB4; PF-4 [Similar Products]
Section Bar
 NCBI Summary for PF4    This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
Section Bar
 UniProt Comments for PF4    PF4: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Apoptosis; Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR3 chemokine receptor binding; heparin binding; protein binding

Biological Process: cytokine and chemokine mediated signaling pathway; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; leukocyte chemotaxis; negative regulation of angiogenesis; negative regulation of cytolysis; negative regulation of megakaryocyte differentiation; negative regulation of MHC class II biosynthetic process; platelet activation; platelet degranulation; positive regulation of cAMP metabolic process; positive regulation of leukocyte chemotaxis; positive regulation of macrophage differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; regulation of cell proliferation; response to lipopolysaccharide
Table BarTOPTable Bar
 Research Articles on PF4    1. Plasma levels of CXCL4 are associated with tumour vascularity.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-PF4 antibodyPathways associated with anti-PF4 antibody
 Reference Product  PubMed Publications
 FGF2 antibody  >16 publications with PF4 and FGF2
 CXCR3 antibody  >14 publications with PF4 and CXCR3
 PROC antibody  >11 publications with PF4 and PROC
 CXCL11 antibody  >5 publications with PF4 and CXCL11
 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Common Pathway antibodies  Common Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
Diseases associated with anti-PF4 antibodyOrgans/Tissues associated with anti-PF4 antibody
 Disease Name  Pubmed Publications
 Thrombocytopenia Antibodies  >423 publications with PF4 and Thrombocytopenia
 Cardiovascular Diseases Antibodies  >352 publications with PF4 and Cardiovascular Diseases
 Thrombosis Antibodies  >286 publications with PF4 and Thrombosis
 Heart Diseases Antibodies  >117 publications with PF4 and Heart Diseases
 Neoplasms Antibodies  >96 publications with PF4 and Neoplasms
 Inflammation Antibodies  >70 publications with PF4 and Inflammation
 Nervous System Diseases Antibodies  >66 publications with PF4 and Nervous System Diseases
 Autoimmune Diseases Antibodies  >58 publications with PF4 and Autoimmune Diseases
 Kidney Diseases Antibodies  >54 publications with PF4 and Kidney Diseases
 Cerebral Infarction Antibodies  >35 publications with PF4 and Cerebral Infarction
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >92 publications with PF4 and Heart
 Bone Antibodies  >70 publications with PF4 and Bone
 Bone Marrow Antibodies  >61 publications with PF4 and Bone Marrow
 Skin Antibodies  >32 publications with PF4 and Skin
 Lung Antibodies  >31 publications with PF4 and Lung
 Embryonic Tissue Antibodies  >18 publications with PF4 and Embryonic Tissue
 Intestine Antibodies  >6 publications with PF4 and Intestine
 Placenta Antibodies  >1 publications with PF4 and Placenta
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions