NP_001123554.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
232,298 Da
NCBI Official Full Name
plexin-B1
NCBI Official Synonym Full Names
plexin B1
NCBI Protein Information
plexin-B1; plexin 5; semaphorin receptor SEP
UniProt Protein Name
Plexin-B1
UniProt Synonym Protein Names
Semaphorin receptor SEP
UniProt Synonym Gene Names
UniProt Entry Name
PLXB1_HUMAN
UniProt Comments for PLXNB1
PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: integral to plasma membrane; plasma membrane; extracellular region; intracellular
Molecular Function: protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; axon guidance; regulation of cell shape; cell migration; positive regulation of axonogenesis; negative regulation of osteoblast proliferation; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis
Research Articles on PLXNB1
Precautions
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Disclaimer
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Products associated with anti-PLXNB1 antibody
Pathways associated with anti-PLXNB1 antibody
Diseases associated with anti-PLXNB1 antibody
Organs/Tissues associated with anti-PLXNB1 antibody
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