NP_036855.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
polymeric immunoglobulin receptor
NCBI Official Synonym Full Names
polymeric immunoglobulin receptor
NCBI Protein Information
polymeric immunoglobulin receptor
UniProt Protein Name
Polymeric immunoglobulin receptor
UniProt Synonym Gene Names
NCBI Summary for PIGR
contains a trinucleotide repeat-rich fragment in the 3' untranslated region that may regulate gene expression [RGD, Feb 2006]
UniProt Comments for PIGR
PIGR: This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 13q13
Cellular Component: extracellular region; extracellular space; integral component of membrane; plasma membrane; receptor complex; recycling endosome membrane; transport vesicle
Molecular Function: epidermal growth factor receptor binding; polymeric immunoglobulin receptor activity
Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; epidermal growth factor receptor signaling pathway; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; receptor clustering; retinal homeostasis
Research Articles on PIGR
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Products associated with anti-PIGR antibody
Pathways associated with anti-PIGR antibody
Diseases associated with anti-PIGR antibody
Organs/Tissues associated with anti-PIGR antibody
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