NP_000362.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
transthyretin
NCBI Official Synonym Full Names
transthyretin
NCBI Official Synonym Symbols
CTS; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651 [Similar Products]
NCBI Protein Information
transthyretin
UniProt Protein Name
Transthyretin
UniProt Synonym Protein Names
ATTR; Prealbumin; TBPA
UniProt Synonym Gene Names
NCBI Summary for PALB
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
UniProt Comments for PALB
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Research Articles on PALB
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Products associated with anti-PALB antibody
Pathways associated with anti-PALB antibody
Diseases associated with anti-PALB antibody
Organs/Tissues associated with anti-PALB antibody
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