Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PINP rightarrow Polyclonal PINP  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • PCCA Antibody
 • Interferon Gamma (IFNg) Recombinant Protein
 • FGFR4 Antibody
 • Complement C3 ELISA Kit
 • Transglutaminase 1, Keratinocyte (TGM1) ELISA Kit
 • 14-3-3 alpha-beta Antibody
 • Benzodiazepine Protein
 • RAB31, member RAS oncogene family ELISA Kit
 • Aconitase 1 (ACO1) Antibody
 • Brain Derived Neurotrophic Factor (BDNF) ELISA Kit
 • Myelin basic protein (MBP) Recombinant Protein
 • WAP four-disulfide core domain protein 2 (WFDC2) Antibody
 • TIMP-2 (TIMP2) ELISA Kit
 • kinesin family member 20B (KIF20B) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PINP antibody :: Rabbit anti-Rat Procollagen I N-Terminal Propeptide (PINP) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2001791 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-PINP antibody
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $245 +1 FREE 8GB USB
0.2 mg  /  $365 +1 FREE 8GB USB
1 mg  /  $870 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Procollagen I N-Terminal Propeptide (PINP), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Procollagen I N-Terminal Propeptide (PINP)

 Product Gene Name   

anti-PINP antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
Biotin Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2005286)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
APC-CY7 Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049982)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
PE Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049983)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
APC-CY7 Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049984)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
Cy3 Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049985)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
FITC Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049986)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
HRP Conjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2049987)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Antibody: Procollagen I N-Terminal Propeptide (PINP) (MBS2001791)
Antigen: Procollagen I N-Terminal Propeptide (PINP) (MBS2097409)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence    PEEYVSPDAE VIG
 3D Structure    ModBase 3D Structure for P02454
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
Section Bar
 Specificity    The antibody is aRabbit polyclonalantibody raised againstPINP. It has been selected for its ability to recognizePINP in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific affinity chromatography followed by Protein A affinity chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
Section Bar
 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Synthetic Peptide, PINP conjugated to OVA
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2049984
Section Bar
 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-PINP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-PINP antibody   

WB; IHC; ICC; IP

 Application Notes for anti-PINP antibody    Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL

Optimal working dilutions must be determined by end user.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PINP. It may not necessarily be applicable to this product.
 NCBI GI #    158711704
 NCBI GeneID    29393
 NCBI Accession #    NP_445756.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_053304.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P02454 [Other Products]
 UniProt Secondary Accession #    P02455; Q63079; A3KNA1 [Other Products]
 UniProt Related Accession #    P02454 [Other Products]
 Molecular Weight    137,953 Da
Table BarTOPTable Bar
 NCBI Official Full Name    collagen alpha-1(I) chain
 NCBI Official Synonym Full Names    collagen type I alpha 1 chain
 NCBI Official Symbol    Col1a1 [Similar Products]
 NCBI Official Synonym Symbols   
COLIA1
[Similar Products]
 NCBI Protein Information    collagen alpha-1(I) chain
 UniProt Protein Name    Collagen alpha-1(I) chain
 UniProt Synonym Protein Names   
Alpha-1 type I collagen
 UniProt Gene Name    Col1a1 [Similar Products]
Section Bar
 NCBI Summary for PINP    extracellular matrix collagen protein [RGD, Feb 2006]
Section Bar
 UniProt Comments for PINP    COL1A1: Type I collagen is a member of group I collagen (fibrillar forming collagen). Defects in COL1A1 are the cause of Caffey disease (CAFFD); also known as infantile cortical hyperostosis. Caffey disease is characterized by an infantile episode of massive subperiosteal new bone formation that typically involves the diaphyses of the long bones, mandible, and clavicles. The involved bones may also appear inflamed, with painful swelling and systemic fever often accompanying the illness. The bone changes usually begin before 5 months of age and resolve before 2 years of age. Defects in COL1A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1); also known as Ehlers-Danlos syndrome gravis. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome. Defects in COL1A1 are the cause of Ehlers-Danlos syndrome type 7A (EDS7A); also known as autosomal dominant Ehlers-Danlos syndrome type VII. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7A is marked by bilateral congenital hip dislocation, hyperlaxity of the joints, and recurrent partial dislocations. Defects in COL1A1 are a cause of osteogenesis imperfecta type 1 (OI1). A dominantly inherited connective tissue disorder characterized by bone fragility and blue sclerae. Osteogenesis imperfecta type 1 is non-deforming with normal height or mild short stature, and no dentinogenesis imperfecta. Defects in COL1A1 are a cause of osteogenesis imperfecta type 2 (OI2); also known as osteogenesis imperfecta congenita. A connective tissue disorder characterized by bone fragility, with many perinatal fractures, severe bowing of long bones, undermineralization, and death in the perinatal period due to respiratory insufficiency. Defects in COL1A1 are a cause of osteogenesis imperfecta type 3 (OI3). A connective tissue disorder characterized by progressively deforming bones, very short stature, a triangular face, severe scoliosis, grayish sclera, and dentinogenesis imperfecta. Defects in COL1A1 are a cause of osteogenesis imperfecta type 4 (OI4); also known as osteogenesis imperfecta with normal sclerae. A connective tissue disorder characterized by moderately short stature, mild to moderate scoliosis, grayish or white sclera and dentinogenesis imperfecta. Genetic variations in COL1A1 are a cause of susceptibility to osteoporosis (OSTEOP); also known as involutional or senile osteoporosis or postmenopausal osteoporosis. Osteoporosis is characterized by reduced bone mass, disruption of bone microarchitecture without alteration in the composition of bone. Osteoporotic bones are more at risk of fracture. A chromosomal aberration involving COL1A1 is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF. Belongs to the fibrillar collagen family.

Protein type: Extracellular matrix; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: collagen; collagen type I trimer; cytoplasm; endoplasmic reticulum; extracellular matrix; extracellular region; extracellular space; Golgi apparatus; proteinaceous extracellular matrix; secretory granule

Molecular Function: extracellular matrix structural constituent; identical protein binding; metal ion binding; platelet-derived growth factor binding; protease binding; protein binding

Biological Process: blood vessel development; collagen biosynthetic process; collagen fibril organization; embryonic skeletal system development; endochondral ossification; extracellular matrix organization; intramembranous ossification; ossification; osteoblast differentiation; positive regulation of cell migration; positive regulation of transcription, DNA-templated; protein transport; response to cAMP; response to corticosteroid stimulus; response to drug; response to estradiol; response to hydrogen peroxide; response to hyperoxia; response to mechanical stimulus; response to nutrient; response to nutrient levels; response to peptide hormone; response to steroid hormone; sensory perception of sound; skeletal morphogenesis; skeletal system development; skin development; skin morphogenesis; visual perception; wound healing
Table BarTOPTable Bar
 Research Articles on PINP    1. the diagnostic value of urinary collagen degradation products in a proteinuria-driven fibrosis rat model, was investigated.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-PINP antibodyPathways associated with anti-PINP antibody
 Reference Product  PubMed Publications
 Col1a2 antibody  >369 publications with PINP and Col1a2
 Col3a1 antibody  >223 publications with PINP and Col3a1
 Col4a1 antibody  >29 publications with PINP and Col4a1
 Col6a3 antibody  >15 publications with PINP and Col6a3
 Col6a1 antibody  >13 publications with PINP and Col6a1
 Col12a1 antibody  >12 publications with PINP and Col12a1
 Itgb1 antibody  >6 publications with PINP and Itgb1
 Col6a2 antibody  >4 publications with PINP and Col6a2
 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Cardiovascular Signaling Pathway antibodies  Cardiovascular Signaling Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
Diseases associated with anti-PINP antibodyOrgans/Tissues associated with anti-PINP antibody
 Disease Name  Pubmed Publications
 Osteogenesis Imperfecta Antibodies  >318 publications with PINP and Osteogenesis Imperfecta
 Fibrosis Antibodies  >261 publications with PINP and Fibrosis
 Osteoporosis Antibodies  >138 publications with PINP and Osteoporosis
 Disease Models, Animal Antibodies  >116 publications with PINP and Disease Models, Animal
 Inflammation Antibodies  >107 publications with PINP and Inflammation
 Liver Diseases Antibodies  >61 publications with PINP and Liver Diseases
 Heart Diseases Antibodies  >43 publications with PINP and Heart Diseases
 Necrosis Antibodies  >43 publications with PINP and Necrosis
 Liver Cirrhosis Antibodies  >42 publications with PINP and Liver Cirrhosis
 Pain Antibodies  >27 publications with PINP and Pain
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >294 publications with PINP and Connective Tissue
 Muscle Antibodies  >186 publications with PINP and Muscle
 Liver Antibodies  >109 publications with PINP and Liver
 Lung Antibodies  >78 publications with PINP and Lung
 Heart Antibodies  >59 publications with PINP and Heart
 Embryonic Tissue Antibodies  >47 publications with PINP and Embryonic Tissue
 Kidney Antibodies  >47 publications with PINP and Kidney
 Tooth Antibodies  >47 publications with PINP and Tooth
 Eye Antibodies  >44 publications with PINP and Eye
 Artery Antibodies  >41 publications with PINP and Artery
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions