Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PDCD1LG1 rightarrow Polyclonal PDCD1LG1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Major allergen Alt a 1 (ALTA1) Recombinant Protein
 • KHSRP Antibody
 • haptoglobin (HP) Antibody
 • TNF alpha ELISA Kit
 • Aspartate Aminotransferase 2 (AST2) Antibody
 • Placenta Growth Factor (PLGF) ELISA Kit
 • Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) Antibody
 • Foot-And-Mouth Disease Virus Antibody (Anti-FMDV) ELISA Kit
 • APC5 (ANAPC5) Antibody
 • Fibronectin, FN ELISA Kit
 • Anti-Ganglioside M3 Antibody (GM3) ELISA Kit
 • ACTH (Adrenocorticotropic Hormone) CLIA Kit
 • Bone Alkaline Phosphatase (BALP) ELISA Kit
 • Insulin Like Growth Factor 1 (IGF-1) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PDCD1LG1 antibody :: Rabbit anti-Mouse Programmed Cell Death Protein 1 Ligand 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2028032 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $315 +1 FREE 8GB USB
1 mg  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1)

 Product Gene Name   

anti-PDCD1LG1 antibody

[Similar Products]
 Matching Pairs    Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
Antigen: Programmed Cell Death Protein 1 (MBS2029139)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
APC-CY7 Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047457)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
PE Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047459)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
APC-CY7 Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047461)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
Cy3 Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047463)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
FITC Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047465)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
HRP Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2047467)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (MBS2028032)
Biotin Conjugated Antibody: Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) (MBS2092488)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for Q9EP73
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
Section Bar
 Specificity    The antibody is a rabbit polyclonal antibody raised against PDCD1LG1. It has beenselected for its ability to recognize PDCD1LG1 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Liquid
 Concentration    200ug/ml (lot specific)
Section Bar
 Fragment    PDCD1LG1 (Ser34~Val241)
 Organism Species    Mus musculus (Mouse)
 Conjugate    No Conjugate
 Immunogen    Recombinant PDCD1LG1 (Ser34~Val241) expressed in E Coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2047461
Section Bar
 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-PDCD1LG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-PDCD1LG1 antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-PDCD1LG1 antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Section Bar
 Western Blot (WB) of anti-PDCD1LG1 antibody    (Figure. Western Blot; Sample: Mouse Heart Tissue.)
anti-PDCD1LG1 antibody Western Blot (WB) (WB) image
Section Bar
 Western Blot (WB) of anti-PDCD1LG1 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-PDCD1LG1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-PDCD1LG1 antibody    (Figure. DAB staining on IHC-P; Samples: Mouse Kidney Tissue.)
anti-PDCD1LG1 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-PDCD1LG1 antibody    (Figure. DAB staining on IHC-P. Samples: Mouse Liver Tissue.)
anti-PDCD1LG1 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PDCD1LG1. It may not necessarily be applicable to this product.
 NCBI GI #    11230798
 NCBI GeneID    60533
 NCBI Accession #    NP_068693.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021893.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9EP73 [Other Products]
 UniProt Related Accession #    Q9EP73 [Other Products]
 Molecular Weight    32,780 Da
Table BarTOPTable Bar
 NCBI Official Full Name    programmed cell death 1 ligand 1
 NCBI Official Synonym Full Names    CD274 antigen
 NCBI Official Symbol    Cd274 [Similar Products]
 NCBI Official Synonym Symbols   
B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik
[Similar Products]
 NCBI Protein Information    programmed cell death 1 ligand 1
 UniProt Protein Name    Programmed cell death 1 ligand 1
 UniProt Synonym Protein Names   
B7 homolog 1; B7-H1; CD_antigen: CD274
 UniProt Gene Name    Cd274 [Similar Products]
 UniProt Synonym Gene Names    B7h1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1 [Similar Products]
Section Bar
 NCBI Summary for PDCD1LG1    The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]
Section Bar
 UniProt Comments for PDCD1LG1    PD-L1: Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19|19 C1

Cellular Component: cell surface; external side of plasma membrane; integral component of membrane; membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cell surface receptor signaling pathway; immune response; negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; negative regulation of interleukin-10 production; negative regulation of T cell proliferation; positive regulation of cell migration; positive regulation of T cell proliferation; response to cytokine; signal transduction; T cell costimulation
Table BarTOPTable Bar
 Research Articles on PDCD1LG1    1. Expression of LAP/TGF-beta1, CD80, CD86 and PD-L1 is significantly increased in tumor-infiltrating B cells (TIL-B) relative to splenic B cells. LAP/TGF-beta1 expression on TIL-B progressively increased from 5.4+/-1.7% on day 8 to 43.1+/-6.1% by day 21 post tumor implantation.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-PDCD1LG1 antibodyDiseases associated with anti-PDCD1LG1 antibody
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 PD-1 Signaling Pathway antibodies  PD-1 Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >111 publications with PDCD1LG1 and Inflammation
 Liver Diseases Antibodies  >88 publications with PDCD1LG1 and Liver Diseases
 Necrosis Antibodies  >74 publications with PDCD1LG1 and Necrosis
 Neoplasms, Experimental Antibodies  >72 publications with PDCD1LG1 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >71 publications with PDCD1LG1 and Nervous System Diseases
 Adenocarcinoma Antibodies  >66 publications with PDCD1LG1 and Adenocarcinoma
 Lung Diseases Antibodies  >46 publications with PDCD1LG1 and Lung Diseases
 Lung Neoplasms Antibodies  >45 publications with PDCD1LG1 and Lung Neoplasms
 Kidney Diseases Antibodies  >44 publications with PDCD1LG1 and Kidney Diseases
 Recurrence Antibodies  >29 publications with PDCD1LG1 and Recurrence
Organs/Tissues associated with anti-PDCD1LG1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >785 publications with PDCD1LG1 and Blood
 Lung Antibodies  >75 publications with PDCD1LG1 and Lung
 Spleen Antibodies  >64 publications with PDCD1LG1 and Spleen
 Bone Marrow Antibodies  >63 publications with PDCD1LG1 and Bone Marrow
 Skin Antibodies  >47 publications with PDCD1LG1 and Skin
 Pancreas Antibodies  >28 publications with PDCD1LG1 and Pancreas
 Heart Antibodies  >25 publications with PDCD1LG1 and Heart
 Stomach Antibodies  >13 publications with PDCD1LG1 and Stomach
 Uterus Antibodies  >7 publications with PDCD1LG1 and Uterus
 Thymus Antibodies  >6 publications with PDCD1LG1 and Thymus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions