NP_032881.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
protein kinase C beta type
NCBI Official Synonym Full Names
protein kinase C, beta
NCBI Official Synonym Symbols
Pkcb; Prkcb1; Prkcb2; PKC-Beta; A130082F03Rik [Similar Products]
NCBI Protein Information
protein kinase C beta type; PKC-B; protein kinase C beta-II; protein kinase C, beta 1
UniProt Protein Name
Protein kinase C beta type
UniProt Synonym Gene Names
UniProt Entry Name
KPCB_MOUSE
UniProt Comments for Prkcb
PKCB iso2: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic receptors. Activates the NF-kappaB signaling pathway in B cells after antigen-receptor signaling. Two splice-variant isoforms have been described.
Protein type: EC 2.7.11.13; Protein kinase, Ser/Thr (non-receptor); Protein kinase, AGC; Kinase, protein; Motility/polarity/chemotaxis; AGC group; PKC family; Alpha subfamily
Cellular Component: centrosome; membrane; brush border membrane; cytoplasm; plasma membrane; cytosol; nucleus
Molecular Function: protein kinase C activity; zinc ion binding; histone binding; metal ion binding; calcium channel regulator activity; nucleotide binding; protein kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; protein kinase C binding; androgen receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; transferase activity, transferring phosphorus-containing groups; chromatin binding; kinase activity; ATP binding
Biological Process: response to drug; positive regulation of I-kappaB kinase/NF-kappaB cascade; B cell activation; transcription, DNA-dependent; apoptosis; immune system process; positive regulation of B cell receptor signaling pathway; negative regulation of insulin receptor signaling pathway; chromatin modification; regulation of dopamine secretion; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; cellular calcium ion homeostasis; regulation of transcription from RNA polymerase II promoter; B cell receptor signaling pathway; positive regulation of angiogenesis; regulation of transcription, DNA-dependent; regulation of growth; calcium ion transport; response to hypoxia; phosphorylation
Research Articles on Prkcb
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Pathways associated with anti-Prkcb antibody
Diseases associated with anti-Prkcb antibody
Organs/Tissues associated with anti-Prkcb antibody
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