Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TGM2 rightarrow Polyclonal TGM2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • TNFSF4 Antibody
 • Osteocalcin (BGLAP) Native Protein
 • Arginine Deiminase (ADI) Recombinant Protein
 • Bacillus anthracis Lethal Factor (Anthrax) Antibody
 • PDGF-B Antibody
 • Pancpin (PANCPIN) ELISA Kit
 • N-terminal pro-brain natriuretic peptide (NT-proBNP) ELISA Kit
 • Adipocyte fatty-acid binding protein (aFABP) ELISA Kit
 • KBTBD7 Antibody
 • Gamma-aminobutyric acid receptor-associated protein (GABARA... Recombinant Protein
 • 5,6-dihydroxyindole-2-carbo xylic acid oxidase (TYRP1) Recombinant Protein
 • ACSS2 Antibody
 • DNA topoisomerase 1 (TOP1) ELISA Kit
 • GNLY ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TGM2 antibody :: Rabbit anti-Human Protein-glutamine gamma-glutamyltransferase 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7004488
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protein-glutamine gamma-glutamyltransferase 2 (TGM2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Protein-glutamine gamma-glutamyltransferase 2 polyclonal Antibody

 Product Synonym Names    Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2; TGM2
 Product Gene Name   

anti-TGM2 antibody

[Similar Products]
 Product Synonym Gene Name    TGM2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    190196
 3D Structure    ModBase 3D Structure for P21980
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
Section Bar
 Immunogen    Recombinant human Protein-glutamine gamma-glutamyltransferase 2 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34543 / sc-19510 / sc-48315 / sc-19509 / sc-48314 / sc-20621
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TGM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-TGM2 antibody

   Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. This protein acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
 Product Categories/Family for anti-TGM2 antibody    Immunology
 Applications Tested/Suitable for anti-TGM2 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-TGM2 antibody    Recommended dilution: WB:1:500-2000
Section Bar
 Western Blot (WB) of anti-TGM2 antibody    Western blot
All lanes: Protein-glutamine gamma-glutamyltransferase 2 antibody at 2ug/ml+HepG2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 78,62,39 kDa
Observed band size: 77 kDa

anti-TGM2 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TGM2. It may not necessarily be applicable to this product.
 NCBI GI #    39777597
 NCBI GeneID    7052
 NCBI Accession #    NP_004604.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004613.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P21980 [Other Products]
 UniProt Secondary Accession #    Q16436; Q6B838; Q9BTN7; Q9UH35; E1P5V9 [Other Products]
 UniProt Related Accession #    P21980 [Other Products]
 Molecular Weight    38,671 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    protein-glutamine gamma-glutamyltransferase 2 isoform a
 NCBI Official Synonym Full Names    transglutaminase 2
 NCBI Official Symbol    TGM2 [Similar Products]
 NCBI Official Synonym Symbols   
TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h
[Similar Products]
 NCBI Protein Information    protein-glutamine gamma-glutamyltransferase 2
 UniProt Protein Name    Protein-glutamine gamma-glutamyltransferase 2
 UniProt Synonym Protein Names   
Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2
 Protein Family    Protein-glutamine gamma-glutamyltransferase
 UniProt Gene Name    TGM2 [Similar Products]
 UniProt Synonym Gene Names    TG(C); TGC; TGase C; TGase H; TGase-2 [Similar Products]
 UniProt Entry Name    TGM2_HUMAN
Section Bar
 NCBI Summary for TGM2    Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TGM2    TGM2: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. . Is the autoantigen in coeliac disease and plays a role in apoptosis, cellular differentiation and matrix stabilisation. Three alternatively spliced isoforms have been described.

Protein type: Transferase; EC 2.3.2.13

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: cytosol; endoplasmic reticulum; focal adhesion; intrinsic to plasma membrane; mitochondrion

Molecular Function: metal ion binding; protein binding; protein-glutamine gamma-glutamyltransferase activity

Biological Process: apoptotic cell clearance; elevation of mitochondrial calcium ion concentration; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); peptide cross-linking; positive regulation of apoptosis; positive regulation of cell adhesion; reduction of endoplasmic reticulum calcium ion concentration
Table BarTOPTable Bar
 Research Articles on TGM2    1. Sequence comparison provided information describing the evolutionary scenario of GTP usage for controlling the activity of TG2.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TGM2 antibodyPathways associated with anti-TGM2 antibody
 Reference Product  PubMed Publications
 ATM antibody  >2 publications with TGM2 and ATM
 FN1 antibody  >2 publications with TGM2 and FN1
 HTT antibody  >1 publications with TGM2 and HTT
 ITGB1 antibody  >1 publications with TGM2 and ITGB1
 Products by Pathway  Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Thromboxane A2 Receptor Signaling Pathway antibodies  Thromboxane A2 Receptor Signaling Pathway Diagram
Diseases associated with anti-TGM2 antibodyOrgans/Tissues associated with anti-TGM2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >12 publications with TGM2 and Inflammation
 Necrosis Antibodies  >6 publications with TGM2 and Necrosis
 Disease Models, Animal Antibodies  >6 publications with TGM2 and Disease Models, Animal
 Lung Neoplasms Antibodies  >6 publications with TGM2 and Lung Neoplasms
 Breast Neoplasms Antibodies  >6 publications with TGM2 and Breast Neoplasms
 Fibrosis Antibodies  >5 publications with TGM2 and Fibrosis
 Brain Neoplasms Antibodies  >5 publications with TGM2 and Brain Neoplasms
 Cardiovascular Diseases Antibodies  >5 publications with TGM2 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >5 publications with TGM2 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with TGM2 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with TGM2 and Lung
 Blood Antibodies  >11 publications with TGM2 and Blood
 Liver Antibodies  >10 publications with TGM2 and Liver
 Brain Antibodies  >10 publications with TGM2 and Brain
 Eye Antibodies  >9 publications with TGM2 and Eye
 Bone Antibodies  >9 publications with TGM2 and Bone
 Skin Antibodies  >7 publications with TGM2 and Skin
 Vascular Antibodies  >6 publications with TGM2 and Vascular
 Connective Tissue Antibodies  >5 publications with TGM2 and Connective Tissue
 Kidney Antibodies  >5 publications with TGM2 and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions