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anti-LOX antibody :: Rabbit anti-Human Protein-lysine 6-oxidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490319 anti-LOX antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protein-lysine 6-oxidase (LOX), Polyclonal Antibody

 Also Known As   

Rabbit anti-human Protein-lysine 6-oxidase polyclonal Antibody, FITC

 Product Synonym Names    Lysyl oxidase; LOX
 Product Gene Name   

anti-LOX antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    153455
 3D Structure    ModBase 3D Structure for P28300
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    FITC
 Immunogen    Recombinant human Protein-lysine 6-oxidase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32409 / sc-32410 / sc-66947
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LOX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LOX antibody

   Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
 Applications Tested/Suitable for anti-LOX antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for LOX. It may not necessarily be applicable to this product.
 NCBI GI #    20149540
 NCBI GeneID    4015
 NCBI Accession #    NP_002308.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002317.6 [Other Products]
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 UniProt Primary Accession #    P28300 [Other Products]
 UniProt Secondary Accession #    Q5FWF0; B2R5Q3 [Other Products]
 UniProt Related Accession #    P28300 [Other Products]
 Molecular Weight    46,944 Da [Similar Products]
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 NCBI Official Full Name    protein-lysine 6-oxidase isoform 1 preproprotein
 NCBI Official Synonym Full Names    lysyl oxidase
 NCBI Official Symbol    LOX [Similar Products]
 NCBI Protein Information    protein-lysine 6-oxidase
 UniProt Protein Name    Protein-lysine 6-oxidase
 UniProt Synonym Protein Names   
Lysyl oxidase
 Protein Family    Protein-lysine 6-oxidase
 UniProt Gene Name    LOX [Similar Products]
 UniProt Entry Name    LYOX_HUMAN
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 NCBI Summary for LOX    This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. [provided by RefSeq, Nov 2015]
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 UniProt Comments for LOX    LOX: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression. Belongs to the lysyl oxidase family.

Protein type: Secreted; Oxidoreductase; EC 1.4.3.13; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: collagen; extracellular region; extracellular space; nucleus; proteinaceous extracellular matrix

Molecular Function: copper ion binding; protein binding; protein-lysine 6-oxidase activity

Biological Process: collagen fibril organization; elastic fiber assembly; extracellular matrix organization and biogenesis; heart development; lung development; protein modification process; response to drug; response to steroid hormone stimulus; wound healing

Disease: Cutis Laxa, Autosomal Recessive, Type Ia
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 Research Articles on LOX    1. LOX gene expression is a predictive factor in hepatocellular liver cancer prognosis and mortality.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LOX antibodyPathways associated with anti-LOX antibody
 Reference Product  PubMed Publications
 LOXL1 antibody  >59 publications with LOX and LOXL1
 SRC antibody  >32 publications with LOX and SRC
 FGF2 antibody  >14 publications with LOX and FGF2
 BMP1 antibody  >8 publications with LOX and BMP1
 FBLN5 antibody  >8 publications with LOX and FBLN5
 SNAI1 antibody  >1 publications with LOX and SNAI1
 EFEMP2 antibody  >1 publications with LOX and EFEMP2
 Products by Pathway  Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Crosslinking Of Collagen Fibrils Pathway antibodies  Crosslinking Of Collagen Fibrils Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-LOX antibodyOrgans/Tissues associated with anti-LOX antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >658 publications with LOX and Inflammation
 Cardiovascular Diseases Antibodies  >621 publications with LOX and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >419 publications with LOX and Disease Models, Animal
 Necrosis Antibodies  >249 publications with LOX and Necrosis
 Heart Diseases Antibodies  >191 publications with LOX and Heart Diseases
 Neoplasms, Experimental Antibodies  >156 publications with LOX and Neoplasms, Experimental
 Hypertension Antibodies  >150 publications with LOX and Hypertension
 Fibrosis Antibodies  >150 publications with LOX and Fibrosis
 Lung Neoplasms Antibodies  >130 publications with LOX and Lung Neoplasms
 Breast Neoplasms Antibodies  >119 publications with LOX and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >770 publications with LOX and Vascular
 Muscle Antibodies  >421 publications with LOX and Muscle
 Brain Antibodies  >390 publications with LOX and Brain
 Lung Antibodies  >301 publications with LOX and Lung
 Heart Antibodies  >280 publications with LOX and Heart
 Liver Antibodies  >260 publications with LOX and Liver
 Bone Antibodies  >248 publications with LOX and Bone
 Skin Antibodies  >185 publications with LOX and Skin
 Kidney Antibodies  >174 publications with LOX and Kidney
 Embryonic Tissue Antibodies  >162 publications with LOX and Embryonic Tissue
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