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anti-PR3 antibody :: Rabbit Proteinase 3 (PR3) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2005777 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Proteinase 3 (PR3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Proteinase 3 (PR3)

 Product Gene Name   

anti-PR3 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
Biotin Conjugated Antibody: Proteinase 3 (PR3) (MBS2004812)
 Matching Pairs    Antibody: Proteinase 3 (PR3) (MBS2005777)
Antigen: Proteinase 3 (PR3) (MBS2010182)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
APC-CY7 Conjugated Antibody: Proteinase 3 (PR3) (MBS2055151)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
PE Conjugated Antibody: Proteinase 3 (PR3) (MBS2055152)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
APC-CY7 Conjugated Antibody: Proteinase 3 (PR3) (MBS2055153)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
Cy3 Conjugated Antibody: Proteinase 3 (PR3) (MBS2055154)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
FITC Conjugated Antibody: Proteinase 3 (PR3) (MBS2055155)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
HRP Conjugated Antibody: Proteinase 3 (PR3) (MBS2055156)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2005777 Technical Datasheet    Technical Datasheet PDF
 3D Structure    ModBase 3D Structure for Q61096
 Clonality    Polyclonal
 Host    Rabbit
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 Purity/Purification    Antigen-specific affinity chromatography followed by Protein A affinity chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Recombinant PR3 (Ala24~Leu249) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2055153
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-PR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PR3 antibody   


 Application Notes for anti-PR3 antibody    Western blotting: 0.5-2 ug/mL;1:500-2000
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200

Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-PR3 antibody    Figure. Western Blot; Sample.

Lane1: Mouse Lung Tissue
Lane2: Mouse Spleen Tissue.)
anti-PR3 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-PR3 antibody    (Figure. Western Blot; Sample: Recombinant PR3 protein.)
anti-PR3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-PR3 antibody    (Figure.DAB staining on IHC-P. Samples: Mouse Tissue)
anti-PR3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PR3. It may not necessarily be applicable to this product.
 NCBI GI #    31981542
 NCBI GeneID    19152
 NCBI Accession #    NP_035308.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_011178.2 [Other Products]
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 UniProt Primary Accession #    Q61096 [Other Products]
 UniProt Secondary Accession #    O08809 [Other Products]
 UniProt Related Accession #    Q61096 [Other Products]
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 NCBI Official Full Name    myeloblastin
 NCBI Official Synonym Full Names    proteinase 3
 NCBI Official Symbol    Prtn3 [Similar Products]
 NCBI Official Synonym Symbols   
PR3; mPR3
[Similar Products]
 NCBI Protein Information    myeloblastin
 UniProt Protein Name    Myeloblastin
 UniProt Synonym Protein Names   
Proteinase 3; PR-3
 UniProt Gene Name    Prtn3 [Similar Products]
 UniProt Synonym Gene Names    PR-3 [Similar Products]
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 UniProt Comments for PR3    PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: Cell cycle regulation; EC; Protease

Chromosomal Location of Human Ortholog: 10 C1|10 39.72 cM

Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane

Molecular Function: enzyme binding; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: collagen catabolic process; negative regulation of phagocytosis; phagocytosis; proteolysis
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 Research Articles on PR3    1. Results provide evidence that proteinase 3 as a new factor involved in non-alcoholic fatty liver disease and insulin resistance.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PR3 antibodyPathways associated with anti-PR3 antibody
 Reference Product  PubMed Publications
 Myb antibody  >2 publications with PR3 and Myb
 Products by Pathway  Pathway Diagram
 Antimicrobial Peptides Pathway antibodies  Antimicrobial Peptides Pathway Diagram
 Common Pathway Of Fibrin Clot Formation antibodies  Common Pathway Of Fibrin Clot Formation Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
Diseases associated with anti-PR3 antibodyOrgans/Tissues associated with anti-PR3 antibody
 Disease Name  Pubmed Publications
 Granulomatosis with Polyangiitis Antibodies  >9 publications with PR3 and Granulomatosis with Polyangiitis
 Cardiovascular Diseases Antibodies  >7 publications with PR3 and Cardiovascular Diseases
 Lung Diseases Antibodies  >5 publications with PR3 and Lung Diseases
 Inflammation Antibodies  >3 publications with PR3 and Inflammation
 Carcinoma Antibodies  >1 publications with PR3 and Carcinoma
 Breast Neoplasms Antibodies  >1 publications with PR3 and Breast Neoplasms
 Neural Tube Defects Antibodies  >1 publications with PR3 and Neural Tube Defects
 Carcinoma, Hepatocellular Antibodies  >1 publications with PR3 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with PR3 and Blood
 Bone Marrow Antibodies  >3 publications with PR3 and Bone Marrow
 Spleen Antibodies  >1 publications with PR3 and Spleen
 Mammary Gland Antibodies  >1 publications with PR3 and Mammary Gland
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