AAH35812.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
133,722 Da
NCBI Official Full Name
Protocadherin 1
NCBI Official Synonym Full Names
protocadherin 1
NCBI Official Synonym Symbols
NCBI Protein Information
protocadherin-1
UniProt Protein Name
Protocadherin-1
UniProt Synonym Protein Names
Cadherin-like protein 1; Protocadherin-42; PC42
UniProt Synonym Gene Names
NCBI Summary for PCDH1
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for PCDH1
PCDH1: a protocadherin protein within the cadherin superfamily. A membrane protein found at cell-cell boundaries. Involved in neural cell adhesion, suggesting a possible role in neuronal development. Contains an extracelllular region with 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component: integral to plasma membrane; intercellular junction; plasma membrane
Biological Process: cell-cell signaling; nervous system development
Research Articles on PCDH1
Precautions
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Disclaimer
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Diseases associated with anti-PCDH1 antibody
Organs/Tissues associated with anti-PCDH1 antibody
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