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anti-S100A7 antibody :: Goat Psoriasin/S100A7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420939
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Psoriasin/S100A7, Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-Psoriasin/S100A7 Antibody

 Product Synonym Names    S100A7; S100 calcium binding protein A7 (psoriasin 1); HGNC: 10497; PSOR1; S100A7c; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); psoriasin 1; Psoriasin; S100A7 antibody; S100 calcium binding protein A7 (psoriasin 1) antibody; HGNC: 10497 antibody; PSOR1 antibody; S100A7c antibody; S100 calcium-binding protein A7 antibody; S100 calcium-binding protein A7 (psoriasin 1) antibody; psoriasin 1 antibody; Psoriasin antibody; Psoriasin; Psoriasin / S100A7
 Product Gene Name   

anti-S100A7 antibody

[Similar Products]
 Antibody/Peptide Pairs    Psoriasin / S100A7 peptide (MBS426582) is used for blocking the activity of Psoriasin/S100A7 antibody (MBS420939)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    HKYTRRDDKI DKP
 OMIM    600353
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-HKYTRRDDKIDKP, from the internal region of the protein sequence according to NP_002954.1.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-S100A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-S100A7 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-S100A7 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
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 Western Blot (WB) of anti-S100A7 antibody    (0.1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-S100A7 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-S100A7 antibody    HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human S100A7 with C-terminal MYC tag probed (0.5ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
anti-S100A7 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for S100A7. It may not necessarily be applicable to this product.
 NCBI GI #    4506769
 NCBI GeneID    6278
 NCBI Accession #    NP_002954.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002963.2 [Other Products]
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 UniProt Secondary Accession #    Q5SY67; Q6FGE3; Q9H1E2 [Other Products]
 UniProt Related Accession #    P31151 [Other Products]
 Molecular Weight    11,471 Da
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 NCBI Official Full Name    S100 calcium-binding protein A7
 NCBI Official Synonym Full Names    S100 calcium binding protein A7
 NCBI Official Symbol    S100A7 [Similar Products]
 NCBI Official Synonym Symbols   
PSOR1; S100A7c
[Similar Products]
 NCBI Protein Information    protein S100-A7
 UniProt Protein Name    Protein S100-A7
 UniProt Synonym Protein Names   
Psoriasin; S100 calcium-binding protein A7
 Protein Family    Protein
 UniProt Gene Name    S100A7 [Similar Products]
 UniProt Synonym Gene Names    PSOR1; S100A7C [Similar Products]
 UniProt Entry Name    S10A7_HUMAN
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 NCBI Summary for S100A7    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
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 UniProt Comments for S100A7    S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular region; focal adhesion; nucleus

Molecular Function: calcium ion binding; protein binding; RAGE receptor binding; zinc ion binding

Biological Process: angiogenesis; defense response to Gram-negative bacterium; epidermis development; innate immune response; keratinocyte differentiation; response to lipopolysaccharide; response to reactive oxygen species; sequestering of metal ion
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 Research Articles on S100A7    1. The presence of S100A7 in the Fallopian tube and its localization at the apical surface of epithelial cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-S100A7 antibodyPathways associated with anti-S100A7 antibody
 Reference Product  PubMed Publications
 RNASE7 antibody  >24 publications with S100A7 and RNASE7
 S100A12 antibody  >15 publications with S100A7 and S100A12
 COPS5 antibody  >6 publications with S100A7 and COPS5
 FABP5 antibody  >5 publications with S100A7 and FABP5
 MYC antibody  >2 publications with S100A7 and MYC
 BRCA1 antibody  >1 publications with S100A7 and BRCA1
 Products by Pathway  Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies  Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram
Diseases associated with anti-S100A7 antibodyOrgans/Tissues associated with anti-S100A7 antibody
 Disease Name  Pubmed Publications
 Psoriasis Antibodies  >92 publications with S100A7 and Psoriasis
 Inflammation Antibodies  >67 publications with S100A7 and Inflammation
 Breast Neoplasms Antibodies  >43 publications with S100A7 and Breast Neoplasms
 Skin Neoplasms Antibodies  >28 publications with S100A7 and Skin Neoplasms
 Dermatitis Antibodies  >16 publications with S100A7 and Dermatitis
 Necrosis Antibodies  >15 publications with S100A7 and Necrosis
 Lung Diseases Antibodies  >12 publications with S100A7 and Lung Diseases
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >12 publications with S100A7 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Lung Neoplasms Antibodies  >11 publications with S100A7 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >9 publications with S100A7 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >169 publications with S100A7 and Skin
 Mouth Antibodies  >20 publications with S100A7 and Mouth
 Brain Antibodies  >8 publications with S100A7 and Brain
 Eye Antibodies  >7 publications with S100A7 and Eye
 Prostate Antibodies  >4 publications with S100A7 and Prostate
 Muscle Antibodies  >2 publications with S100A7 and Muscle
 Larynx Antibodies  >2 publications with S100A7 and Larynx
 Uterus Antibodies  >1 publications with S100A7 and Uterus
 Pharynx Antibodies  >1 publications with S100A7 and Pharynx
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