NP_003357.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,443 Da
NCBI Official Full Name
cytochrome b-c1 complex subunit 2, mitochondrial
NCBI Official Synonym Full Names
ubiquinol-cytochrome c reductase core protein II
NCBI Protein Information
cytochrome b-c1 complex subunit 2, mitochondrial
UniProt Protein Name
Cytochrome b-c1 complex subunit 2, mitochondrial
UniProt Synonym Protein Names
Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2
UniProt Entry Name
QCR2_HUMAN
NCBI Summary for QCR2 / UQCRC2
The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]
UniProt Comments for QCR2 / UQCRC2
UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
Protein type: EC 1.10.2.2; Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation
Chromosomal Location of Human Ortholog: 16p12
Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrion; myelin sheath; nucleoplasm
Molecular Function: metalloendopeptidase activity; protein binding; protein complex binding; zinc ion binding
Biological Process: aerobic respiration; cellular metabolic process; mitochondrial electron transport, ubiquinol to cytochrome c; oxidative phosphorylation; protein processing
Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5
Research Articles on QCR2 / UQCRC2
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Products associated with anti-QCR2 / UQCRC2 antibody
Pathways associated with anti-QCR2 / UQCRC2 antibody
Diseases associated with anti-QCR2 / UQCRC2 antibody
Organs/Tissues associated with anti-QCR2 / UQCRC2 antibody
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