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anti-QKI antibody :: Rabbit anti-Human QKI Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044097
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

QKI, Polyclonal Antibody

★Popular Item★
 Also Known As   

QKI Antibody

 Product Synonym Names    Protein quaking; Hqk; HqkI; QKI; HKQ
 Product Gene Name   

anti-QKI antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609590
 3D Structure    ModBase 3D Structure for Q96PU8
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Protein quaking protein (1-341AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103851
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-QKI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-QKI antibody

   RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
 Applications Tested/Suitable for anti-QKI antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-QKI antibody    Western blot
All lanes: QKI antibody at 1.92ug/ml
Lane 1:HL-60 whole cell lysate
Lane 2:Hela whole cell lysate
Lane 3:K562 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 38,37,36 kDa
Observed band size: 38 kDa,70 kDa

anti-QKI antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-QKI antibody    Immunohistochemistry of paraffin-embedded human testis using MBS7044097 at dilution 1:100
anti-QKI antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-QKI antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044097 at dilution 1:100
anti-QKI antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for QKI. It may not necessarily be applicable to this product.
 NCBI GI #    666637982
 NCBI GeneID    9444
 NCBI Accession #    NP_001288014.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001301085.1 [Other Products]
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 UniProt Primary Accession #    Q96PU8 [Other Products]
 UniProt Secondary Accession #    Q2I375; Q5MJQ1; Q969L9; Q96EJ3; Q96KA3; Q96PU6; Q96PU7; Q9P0X6; Q9P0X7; Q9P0X8; Q9P0X9 [Other Products]
 UniProt Related Accession #    Q96PU8 [Other Products]
 Molecular Weight    35,131 Da
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 NCBI Official Full Name    protein quaking isoform 5
 NCBI Official Synonym Full Names    QKI, KH domain containing RNA binding
 NCBI Official Symbol    QKI [Similar Products]
 NCBI Official Synonym Symbols   
QK; Hqk; QK1; QK3; hqkI
[Similar Products]
 NCBI Protein Information    protein quaking
 UniProt Protein Name    Protein quaking
 Protein Family    Protein quaking
 UniProt Gene Name    QKI [Similar Products]
 UniProt Synonym Gene Names    HKQ; Hqk; HqkI [Similar Products]
 UniProt Entry Name    QKI_HUMAN
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 NCBI Summary for QKI    The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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 UniProt Comments for QKI    RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor ().
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 Research Articles on QKI    1. QKI has a role in posttranscriptionally guiding macrophage identity and function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-QKI antibodyDiseases associated with anti-QKI antibody
 Products by Pathway  Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 Disease Name  Pubmed Publications
 Glioma Antibodies  >13 publications with QKI and Glioma
 Disease Models, Animal Antibodies  >6 publications with QKI and Disease Models, Animal
 Chromosome Aberrations Antibodies  >6 publications with QKI and Chromosome Aberrations
 Breast Neoplasms Antibodies  >4 publications with QKI and Breast Neoplasms
 Neoplasm Invasiveness Antibodies  >4 publications with QKI and Neoplasm Invasiveness
 Heart Diseases Antibodies  >4 publications with QKI and Heart Diseases
 Inflammation Antibodies  >3 publications with QKI and Inflammation
 Lung Neoplasms Antibodies  >3 publications with QKI and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with QKI and Carcinoma, Hepatocellular
 Neoplasm Metastasis Antibodies  >2 publications with QKI and Neoplasm Metastasis
Organs/Tissues associated with anti-QKI antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >43 publications with QKI and Brain
 Nerve Antibodies  >31 publications with QKI and Nerve
 Blood Antibodies  >14 publications with QKI and Blood
 Embryonic Tissue Antibodies  >11 publications with QKI and Embryonic Tissue
 Heart Antibodies  >8 publications with QKI and Heart
 Vascular Antibodies  >8 publications with QKI and Vascular
 Muscle Antibodies  >7 publications with QKI and Muscle
 Lung Antibodies  >5 publications with QKI and Lung
 Mouth Antibodies  >3 publications with QKI and Mouth
 Testis Antibodies  >3 publications with QKI and Testis
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