NP_036546.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,361 Da
NCBI Official Full Name
rab3 GTPase-activating protein non-catalytic subunit
NCBI Official Synonym Full Names
RAB3 GTPase activating non-catalytic protein subunit 2
NCBI Official Synonym Symbols
p150; SPG69; WARBM2; RAB3GAP150; RAB3-GAP150 [Similar Products]
NCBI Protein Information
rab3 GTPase-activating protein non-catalytic subunit
UniProt Protein Name
Rab3 GTPase-activating protein non-catalytic subunit
UniProt Synonym Protein Names
RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit
UniProt Synonym Gene Names
NCBI Summary for RAB3GAP2
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]
UniProt Comments for RAB3GAP2
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Research Articles on RAB3GAP2
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Products associated with anti-RAB3GAP2 antibody
Pathways associated with anti-RAB3GAP2 antibody
Diseases associated with anti-RAB3GAP2 antibody
Organs/Tissues associated with anti-RAB3GAP2 antibody
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