EAW85794.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
RAB40C, member RAS oncogene family, isoform CRA_a
NCBI Official Synonym Full Names
RAB40C, member RAS oncogene family
NCBI Official Synonym Symbols
NCBI Protein Information
ras-related protein Rab-40C; RAR like; RAS-like GTPase; rar-like protein; RAR (RAS like GTPASE) like; RAS-like, family 8, member C; SOCS box-containing protein RAR3; ras-like protein family member 8C
UniProt Protein Name
Ras-related protein Rab-40C
UniProt Synonym Protein Names
Rar-like protein; Ras-like protein family member 8C; SOCS box-containing protein RAR3
UniProt Synonym Gene Names
UniProt Entry Name
RB40C_HUMAN
UniProt Comments for RAB40C
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Ref.4
Pathway: Protein modification; protein ubiquitination.
Subunit structure: Component of the probable SCF-like ECS(RAB40C) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and RAB40C. Interacts with CUL5, RNF7, TCEB1 and TCEB2. Ref.4
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side
Potential.
Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes
By similarity.
Sequence similarities: Belongs to the small GTPase superfamily. Rab family.Contains 1 SOCS box domain.
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Diseases associated with anti-RAB40C antibody
Organs/Tissues associated with anti-RAB40C antibody
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