Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow RAMP1 rightarrow Polyclonal RAMP1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Collagen Type IX alpha1 (COL9a1) ELISA Kit
 • NKX2-1 Antibody
 • Total prostate s pecific antigen (TPSA) ELISA Kit
 • TUBB3 - Tubulin Beta 3 Antibody
 • Mothers Against Decapentaplegic Homolog 1 (SMAD1) ELISA Kit
 • PLA2G3 Antibody
 • Vitamin D3 (VD3) ELISA Kit
 • VACCINIA VIRUS Antibody
 • E. coli (SLT-2, STX-2) beta subunit Antibody
 • Keratin 4 (KRT4) ELISA Kit
 • Cancer Antigen CA125 Reagent
 • Na+-K+-ATPase (Na-K ATPase) ELISA Kit
 • Hepatitis C Virus 4th Generation (HCV) Recombinant Protein
 • NK3 homeobox 1 (NKX3-1) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-RAMP1 antibody :: Goat anti-Rat RAMP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS622973 anti-RAMP1 antibody
Unit / Price
0.1 mg  /  $560 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAMP1, Polyclonal Antibody

 Also Known As   

RAMP1 (Receptor Activity Modifying Protein1, Receptor Activity Modifying Protein 1 [Precursor], Receptor (G Protein-coupled) Activity Modifying Protein 1, Calcitonin Receptor-like Receptor Activity Modifying Protein 1, CRLR Activity Modifying Protein 1)

 Product Synonym Names    Anti -RAMP1 (Receptor Activity Modifying Protein1, Receptor Activity Modifying Protein 1 [Precursor], Receptor (G Protein-coupled) Activity Modifying Protein 1, Calcitonin Receptor-like Receptor Activity Modifying Protein 1, CRLR Activity Modifying Protein 1)
 Product Gene Name   

anti-RAMP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 2; NC_000002.11 (238768187..238820756). Location: 2q36-q37.1
 OMIM    605153
 3D Structure    ModBase 3D Structure for O60894
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
 Species Reactivity    Rat
Section Bar
 Specificity    Recognizes rat Ramp1. Sequence homology: human, mouse.
 Purity/Purification    Affinity Purified
Purified by affinity chromatography.
 Form/Format    Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Section Bar
 Immunogen    Synthetic peptide corresponding to C-DYQSKRTEGIV, from the C-Terminus of rat Ramp1 (NP_058590.1; NP_848488.2).
Section Bar
 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-RAMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-RAMP1 antibody

   RAMPS may be involved in the transport of CRLR to the plasma membrane. RAMP1 (human, mouse, rat 148 aa) presents the CRLR receptor as a glycoprotein that function as CGRP receptor. RAMP1 is expressed in many tissues, including the uterus, bladder, brain, pancreas, and GI tract. CRLR and RAMP1 are not co-expressed in all tissues suggesting that their co-expression may define which cells express functional CGRP receptors. RAMP2 (human 175 aa; rat 182 aa, and mouse 189 aa)-transported receptors are core-glycosylated and function as ADM receptor. It is expressed in the lung, breast, immune system and fetal tissues. RAMP3 is most abundant in the kidney and lung.
 Product Categories/Family for anti-RAMP1 antibody    Antibodies; Abs to Transport Proteins
 Applications Tested/Suitable for anti-RAMP1 antibody   

Western Blot (WB)

 Application Notes for anti-RAMP1 antibody    Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:64,000
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RAMP1. It may not necessarily be applicable to this product.
 NCBI GI #    5032019
 NCBI GeneID    10267
 NCBI Accession #    NP_005846.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005855.2 [Other Products]
Section Bar
 UniProt Primary Accession #    O60894 [Other Products]
 UniProt Secondary Accession #    Q6FGS5 [Other Products]
 UniProt Related Accession #    O60894; Q53SN3; Q53T50 [Other Products]
 Molecular Weight    16,988 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    receptor activity-modifying protein 1
 NCBI Official Synonym Full Names    receptor (G protein-coupled) activity modifying protein 1
 NCBI Official Symbol    RAMP1 [Similar Products]
 NCBI Official Synonym Symbols   
RAMP1
[Similar Products]
 NCBI Protein Information    receptor activity-modifying protein 1; OTTHUMP00000164475; CRLR activity-modifying protein 1; receptor activity modifying protein 1; receptor (calcitonin) activity modifying protein 1; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1
 UniProt Protein Name    Receptor activity-modifying protein 1
 UniProt Synonym Protein Names   
Calcitonin-receptor-like receptor activity-modifying protein 1
 Protein Family    Receptor activity-modifying protein
 UniProt Gene Name    RAMP1 [Similar Products]
 UniProt Entry Name    RAMP1_HUMAN
Section Bar
 NCBI Summary for RAMP1    The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]
Section Bar
 UniProt Comments for RAMP1    RAMP1: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. Belongs to the RAMP family.

Protein type: Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q36-q37.1

Cellular Component: extracellular space; cell surface; integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; calcitonin receptor binding; coreceptor activity; receptor activity; protein transporter activity; calcitonin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; intracellular protein transport; protein transport; positive regulation of protein amino acid glycosylation; receptor internalization; calcium ion transport; positive regulation of cAMP biosynthetic process; angiogenesis; regulation of G-protein coupled receptor protein signaling pathway
Table BarTOPTable Bar
 Research Articles on RAMP1    1. lower expression in bronchial biopsies from subjects with asthma
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-RAMP1 antibodyPathways associated with anti-RAMP1 antibody
 Reference Product  PubMed Publications
 CALCRL antibody  >91 publications with RAMP1 and CALCRL
 IAPP antibody  >26 publications with RAMP1 and IAPP
 CALCA antibody  >1 publications with RAMP1 and CALCA
 Products by Pathway  Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
Diseases associated with anti-RAMP1 antibodyOrgans/Tissues associated with anti-RAMP1 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >28 publications with RAMP1 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >25 publications with RAMP1 and Vascular Diseases
 Hypertension Antibodies  >21 publications with RAMP1 and Hypertension
 Heart Diseases Antibodies  >12 publications with RAMP1 and Heart Diseases
 Pain Antibodies  >12 publications with RAMP1 and Pain
 Neoplasms Antibodies  >9 publications with RAMP1 and Neoplasms
 Myocardial Ischemia Antibodies  >9 publications with RAMP1 and Myocardial Ischemia
 Inflammation Antibodies  >8 publications with RAMP1 and Inflammation
 Fibrosis Antibodies  >7 publications with RAMP1 and Fibrosis
 Hypertrophy Antibodies  >6 publications with RAMP1 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >48 publications with RAMP1 and Muscle
 Heart Antibodies  >32 publications with RAMP1 and Heart
 Brain Antibodies  >31 publications with RAMP1 and Brain
 Kidney Antibodies  >16 publications with RAMP1 and Kidney
 Uterus Antibodies  >10 publications with RAMP1 and Uterus
 Bone Antibodies  >10 publications with RAMP1 and Bone
 Lung Antibodies  >9 publications with RAMP1 and Lung
 Placenta Antibodies  >8 publications with RAMP1 and Placenta
 Connective Tissue Antibodies  >6 publications with RAMP1 and Connective Tissue
 Ovary Antibodies  >4 publications with RAMP1 and Ovary
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions