NP_001005765.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ras-related protein Rap-1A
NCBI Official Synonym Full Names
RAP1A, member of RAS oncogene family
NCBI Official Synonym Symbols
RAP-1A; rap 1A; MGC93785; MGC94873 [Similar Products]
NCBI Protein Information
ras-related protein Rap-1A; RAS-related protein 1a; ras-related protein Krev-1
UniProt Protein Name
Ras-related protein Rap-1A
UniProt Synonym Protein Names
Ras-related protein Krev-1
UniProt Synonym Gene Names
UniProt Entry Name
RAP1A_RAT
UniProt Comments for Rap1a
RAP1A: a small G protein of the Ras family with tumor suppressor activity. Induces morphological reversion of a cell line transformed by a Ras oncogene. Activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2 in a cAMP-dependent manner, and GFR. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Interacts with SGSM1, SGSM2 and SGSM3.
Protein type: Tumor suppressor; G protein; G protein, monomeric, Ras; G protein, monomeric; Motility/polarity/chemotaxis
Cellular Component: neuron projection; perinuclear region of cytoplasm; cytoplasm; early endosome; late endosome; plasma membrane; cell junction; cytosol; myelin sheath
Molecular Function: GTPase activity; Rap guanyl-nucleotide exchange factor activity; Ras GTPase binding; GTP binding; protein complex binding; protein transporter activity
Biological Process: microvillus biogenesis; protein transport; metabolic process; positive regulation of protein kinase activity; small GTPase mediated signal transduction; Rap protein signal transduction
Research Articles on Rap1a
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Pathways associated with anti-Rap1a antibody
Diseases associated with anti-Rap1a antibody
Organs/Tissues associated with anti-Rap1a antibody
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