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anti-RBM25 antibody :: Rabbit RBM25 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7603404 anti-RBM25 antibody
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RBM25, Polyclonal Antibody

 Also Known As   

RBM25 Rabbit Polyclonal

 Product Gene Name   

anti-RBM25 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612427
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >=95% as determined by SDS-PAGE
Immunogen Affinity Purified
 Form/Format    Liquid
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 Immunogen    RNA binding motif protein 25
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 Preparation and Storage    PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RBM25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RBM25 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for RBM25. It may not necessarily be applicable to this product.
 NCBI GI #    219520438
 NCBI GeneID    58517
 NCBI Accession #    AAI44408.1 [Other Products]
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 UniProt Secondary Accession #    Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9; A0PJL9; B2RNA8; B3KT03 [Other Products]
 UniProt Related Accession #    P49756 [Other Products]
 Molecular Weight    17,953 Da
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 NCBI Official Full Name    RBM25 protein
 NCBI Official Synonym Full Names    RNA binding motif protein 25
 NCBI Official Symbol    RBM25 [Similar Products]
 NCBI Official Synonym Symbols   
S164; NET52; RNPC7; Snu71; RED120; fSAP94
[Similar Products]
 NCBI Protein Information    RNA-binding protein 25
 UniProt Protein Name    RNA-binding protein 25
 UniProt Synonym Protein Names   
Arg/Glu/Asp-rich protein of 120 kDa; RED120; Protein S164; RNA-binding motif protein 25; RNA-binding region-containing protein 7
 Protein Family    RNA-binding protein
 UniProt Gene Name    RBM25 [Similar Products]
 UniProt Synonym Gene Names    RNPC7; RED120 [Similar Products]
 UniProt Entry Name    RBM25_HUMAN
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 UniProt Comments for RBM25    RBM25: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: cytoplasm; nuclear speck; nucleoplasm; spliceosome

Molecular Function: mRNA binding; nucleotide binding; protein binding

Biological Process: mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome; regulation of apoptosis; RNA splicing
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 Research Articles on RBM25    1. Structure-guided mutagenesis reveals a positively charged nucleic-acid-binding surface in the RBM25 PWI domain
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-RBM25 antibodyDiseases associated with anti-RBM25 antibody
 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >2 publications with RBM25 and Cardiovascular Diseases
 Liver Diseases Antibodies  >2 publications with RBM25 and Liver Diseases
 Heart Diseases Antibodies  >2 publications with RBM25 and Heart Diseases
 Fibrosis Antibodies  >1 publications with RBM25 and Fibrosis
 Necrosis Antibodies  >1 publications with RBM25 and Necrosis
 Poisoning Antibodies  >1 publications with RBM25 and Poisoning
Organs/Tissues associated with anti-RBM25 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with RBM25 and Liver
 Bone Antibodies  >3 publications with RBM25 and Bone
 Bone Marrow Antibodies  >3 publications with RBM25 and Bone Marrow
 Heart Antibodies  >2 publications with RBM25 and Heart
 Ovary Antibodies  >1 publications with RBM25 and Ovary
 Pancreas Antibodies  >1 publications with RBM25 and Pancreas
 Muscle Antibodies  >1 publications with RBM25 and Muscle
 Blood Antibodies  >1 publications with RBM25 and Blood
 Embryonic Tissue Antibodies  >1 publications with RBM25 and Embryonic Tissue
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