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anti-RDM1 antibody :: Rabbit anti-Human RDM1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1493169
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RDM1, Polyclonal Antibody

★Popular Item★
 Also Known As   

RDM1 Antibody

 Product Synonym Names    RAD52 homolog B; RDM1; RAD52B
 Product Gene Name   

anti-RDM1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612896
 3D Structure    ModBase 3D Structure for Q8NG50
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human RAD52 motif-containing protein 1 protein (125-284aa)
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RDM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RDM1 antibody

   May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.
 Applications Tested/Suitable for anti-RDM1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-RDM1 antibody    Recommended dilution: WB:1:200-1000
IHC:1:20-1:200
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 Western Blot (WB) of anti-RDM1 antibody    Western blot
All lanes: RDM1 antibody at 4ug/ml
Lane 1:PC-3 whole cell lysate
Lane 2:MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 32,30,16,14,29,26,9,13,19,27 kDa
Observed band size: 32 kDa

anti-RDM1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-RDM1 antibody    Immunohistochemistry of paraffin-embedded human testis using MBS1493169 at dilution 1:100
anti-RDM1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for RDM1. It may not necessarily be applicable to this product.
 NCBI GI #    77873934
 NCBI GeneID    201299
 NCBI Accession #    NP_001030008.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001034836.1 [Other Products]
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 UniProt Primary Accession #    Q8NG50 [Other Products]
 UniProt Secondary Accession #    A0JP55; A8MV46; A8MY68; A8MZ92; A8RCS5; A8RCT0; A8RCT5; A8RCT8; A8RCU3; A8RCU8; A8RCW0 [Other Products]
 UniProt Related Accession #    Q8NG50 [Other Products]
 Molecular Weight    26,382 Da
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 NCBI Official Full Name    RAD52 motif-containing protein 1 isoform 2
 NCBI Official Synonym Full Names    RAD52 motif containing 1
 NCBI Official Symbol    RDM1 [Similar Products]
 NCBI Official Synonym Symbols   
RAD52B
[Similar Products]
 NCBI Protein Information    RAD52 motif-containing protein 1
 UniProt Protein Name    RAD52 motif-containing protein 1
 UniProt Synonym Protein Names   
RAD52 homolog B
 Protein Family    RAD52 motif-containing protein
 UniProt Gene Name    RDM1 [Similar Products]
 UniProt Synonym Gene Names    RAD52B [Similar Products]
 UniProt Entry Name    RDM1_HUMAN
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 NCBI Summary for RDM1    This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RDM1    RDM1: May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. 11 isoforms of the human protein are produced by alternative promoter.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: Cajal body; cytoplasm; nucleolus; PML body

Molecular Function: DNA binding; nucleotide binding; protein binding; RNA binding
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 Research Articles on RDM1    1. The identification of 11 human cDNAs encoding RDM1 protein isoforms which is generated by alternative pre-mRNA splicing and differential usage of two translational start sites.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RDM1 antibodyDiseases associated with anti-RDM1 antibody
 Reference Product  PubMed Publications
 RAD52 antibody  >3 publications with RDM1 and RAD52
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with RDM1 and Breast Neoplasms
Organs/Tissues associated with anti-RDM1 antibody
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with RDM1 and Testis
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