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anti-REG4 antibody :: Rabbit REG4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8241276
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

REG4, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-REG4 Antibody

 Product Synonym Names    GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
 Product Gene Name   

anti-REG4 antibody

[Similar Products]
 Antibody/Peptide Pairs    REG4 peptide (MBS8215505) is used for blocking the activity of REG4 antibody (MBS8241276)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609846
 3D Structure    ModBase 3D Structure for Q9BYZ8
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Porcine
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 Specificity    Recognizes endogenous levels of REG4 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human REG4. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4C. Upon delivery aliquot and store at -20C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-REG4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-REG4 antibody

   Rabbit polyclonal antibody to REG4
 Applications Tested/Suitable for anti-REG4 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-REG4 antibody    WB (1/500 - 1/1000)
IHC (1/100 - 1/200)
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 Western Blot (WB) of anti-REG4 antibody    Western blot analysis of REG4 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates.
anti-REG4 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-REG4 antibody    Immunohistochemical analysis of REG4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w
anti-REG4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for REG4. It may not necessarily be applicable to this product.
 NCBI GI #    226823233
 NCBI GeneID    83998
 NCBI Accession #    NP_001152824.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001159352.1 [Other Products]
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 UniProt Primary Accession #    Q9BYZ8 [Other Products]
 UniProt Secondary Accession #    Q8NER6; Q8NER7 [Other Products]
 UniProt Related Accession #    Q9BYZ8 [Other Products]
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 NCBI Official Full Name    regenerating islet-derived protein 4 isoform 1
 NCBI Official Synonym Full Names    regenerating islet-derived family, member 4
 NCBI Official Symbol    REG4 [Similar Products]
 NCBI Official Synonym Symbols   
GISP; RELP; REG-IV
[Similar Products]
 NCBI Protein Information    regenerating islet-derived protein 4
 UniProt Protein Name    Regenerating islet-derived protein 4
 UniProt Synonym Protein Names   
Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
 Protein Family    Regenerating islet-derived protein
 UniProt Gene Name    REG4 [Similar Products]
 UniProt Synonym Gene Names    GISP; RELP; REG-4; Reg IV [Similar Products]
 UniProt Entry Name    REG4_HUMAN
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 UniProt Comments for REG4    REG4: Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13.1-p12

Cellular Component: cytoplasm; extracellular region

Molecular Function: heparin binding; calcium ion binding
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 Research Articles on REG4    1. Colorectal tumor patients with Reg4- and MMP-7-positive tumors had extremely poor overall survival.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-REG4 antibodyDiseases associated with anti-REG4 antibody
 Reference Product  PubMed Publications
 CDX2 antibody  >7 publications with REG4 and CDX2
 OLFM4 antibody  >6 publications with REG4 and OLFM4
 CLDN18 antibody  >4 publications with REG4 and CLDN18
 LGALS4 antibody  >2 publications with REG4 and LGALS4
 ADAM9 antibody  >1 publications with REG4 and ADAM9
 GLI1 antibody  >1 publications with REG4 and GLI1
 Disease Name  Pubmed Publications
 Gastrointestinal Diseases Antibodies  >58 publications with REG4 and Gastrointestinal Diseases
 Carcinoma Antibodies  >34 publications with REG4 and Carcinoma
 Stomach Neoplasms Antibodies  >22 publications with REG4 and Stomach Neoplasms
 Neoplasm Metastasis Antibodies  >10 publications with REG4 and Neoplasm Metastasis
 Colonic Neoplasms Antibodies  >8 publications with REG4 and Colonic Neoplasms
 Cell Transformation, Neoplastic Antibodies  >6 publications with REG4 and Cell Transformation, Neoplastic
 Liver Neoplasms Antibodies  >4 publications with REG4 and Liver Neoplasms
 Inflammation Antibodies  >4 publications with REG4 and Inflammation
 Prostatic Neoplasms Antibodies  >4 publications with REG4 and Prostatic Neoplasms
 Precancerous Conditions Antibodies  >3 publications with REG4 and Precancerous Conditions
Organs/Tissues associated with anti-REG4 antibody
 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >26 publications with REG4 and Stomach
 Intestine Antibodies  >22 publications with REG4 and Intestine
 Pancreas Antibodies  >10 publications with REG4 and Pancreas
 Prostate Antibodies  >5 publications with REG4 and Prostate
 Lung Antibodies  >3 publications with REG4 and Lung
 Mammary Gland Antibodies  >1 publications with REG4 and Mammary Gland
 Ovary Antibodies  >1 publications with REG4 and Ovary
 Ascites Antibodies  >1 publications with REG4 and Ascites
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