Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow REL rightarrow Polyclonal REL  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Triiodothyronine Antibody
 • Proteasome subunit beta type-2 (PSMB2) Antibody
 • UBIQUITIN (UBA52) Antibody
 • High affinity immunoglobulin epsilon receptor subunit beta (... ELISA Kit
 • Angiotensin I Converting Enzyme 2 (ACE2) ELISA Kit
 • CDC25 Antibody
 • Mouse IgM Isotype Control Isotype Control
 • Angiopoietin Like Protein 4 (ANGPTL4) ELISA Kit
 • BolA-like protein 2 (BOLA2) Recombinant Protein
 • CD20 Antibody
 • MMP7 Antibody
 • Abl Interactor 1 (ABI1) ELISA Kit
 • Dicer-1 (Dcr-1) ELISA Kit
 • Mammalian target of rapamycin (mTOR) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-REL antibody :: Goat REL Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422318
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

REL, Polyclonal Antibody

 Also Known As   

Goat anti-REL Antibody

 Product Synonym Names    REL; v-rel reticuloendotheliosis viral oncogene homolog (avian); C-Rel; C-Rel proto-oncogene protein; oncogene REL, avian reticuloendotheliosis; v-rel avian reticuloendotheliosis viral oncogene homolog; v-rel reticuloendotheliosis viral oncogene homolog; C-Rel antibody; C-Rel proto-oncogene protein antibody; oncogene REL; avian reticuloendotheliosis antibody; v-rel avian reticuloendotheliosis viral oncogene homolog antibody; v-rel reticuloendotheliosis viral oncogene homolog antibody; v-rel reticuloendotheliosis viral oncogene homolog (avian) antibody; REL antibody
 Product Gene Name   

anti-REL antibody

[Similar Products]
 Antibody/Peptide Pairs    REL peptide (MBS427223) is used for blocking the activity of REL antibody (MBS422318)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence    NDLNASNACI YN
 OMIM    164910
Section Bar
 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Dog
Section Bar
 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
Section Bar
 Immunogen    Peptide with sequence NDLNASNACIYN, from the internal region of the protein sequence according to NP_002899.1.
 Epitope    Internal region
Section Bar
 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-REL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-REL antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-REL antibody    Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 70kDa band observed in Human Spleen and Human Peripheral Blood Mononucleocytes lysates (calculated MW of 68.5kDa according to NP_002899.1). Recommended concentration: 0.5-2ug/ml.
Section Bar
 Western Blot (WB) of anti-REL antibody    (0.5ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-REL antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for REL. It may not necessarily be applicable to this product.
 NCBI GI #    4506473
 NCBI GeneID    5966
 NCBI Accession #    NP_002899.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002908.3 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q17RU2; Q2PNZ7; Q6LDY0 [Other Products]
 UniProt Related Accession #    Q04864 [Other Products]
 Molecular Weight    65,225 Da
Table BarTOPTable Bar
 NCBI Official Full Name    proto-oncogene c-Rel isoform 1
 NCBI Official Synonym Full Names    REL proto-oncogene, NF-kB subunit
 NCBI Official Symbol    REL [Similar Products]
 NCBI Official Synonym Symbols   
C-Rel
[Similar Products]
 NCBI Protein Information    proto-oncogene c-Rel
 UniProt Protein Name    Proto-oncogene c-Rel
 Protein Family    Relaxin
 UniProt Gene Name    REL [Similar Products]
 UniProt Entry Name    REL_HUMAN
Section Bar
 NCBI Summary for REL    This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Section Bar
 UniProt Comments for REL    REL: a proto-oncogenic transcription factor of the nuclear factor-kappaB (NFkB) group. There are five NFkB proteins in mammals (RelA/NFkB-p65, RelB, c-Rel, NF-_B1/NFkB-p105, and NF-_B2/NFkB-p100). They form a variety of homodimers and heterodimers, each of which activates its own characteristic set of genes. May play a role in differentiation and lymphopoiesis.

Protein type: Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 2p13-p12

Cellular Component: cytosol; nucleoplasm; nucleus; transcription factor complex

Molecular Function: chromatin binding; protein binding; transcription factor activity

Biological Process: I-kappaB kinase/NF-kappaB cascade; inflammatory response; innate immune response; negative regulation of interferon-beta production; negative regulation of transcription from RNA polymerase II promoter; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription from RNA polymerase II promoter; response to cytokine stimulus; transcription from RNA polymerase II promoter
Table BarTOPTable Bar
 Research Articles on REL    1. Thus, our studies support a role for c-Rel in processes crucial for keratinocyte integrity and malignant transformation such as adhesion and migration.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products related to Goat anti-REL Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS1196595  Recombinant Arthrobacter chlorophenolicus Peptide chain release factor 2 (prfB)  MBS1290092  Recombinant Chicken Nuclear factor erythroid 2-related factor 1 (NFE2L1), partial
 MBS1052137  Recombinant Methylobacterium sp. Peptide chain release factor 1 (prfA)  MBS946935  Rat Kallikrein-12, KLK12 ELISA Kit
 MBS7238486  Sheep Autophagy-related protein 2 homolog A (ATG2A) ELISA Kit  MBS1452578  Recombinant Debaryomyces hansenii Autophagy-related protein 27 (ATG27)
 MBS059790  Cat Gonadotropin Releasing Hormone ELISA Kit  MBS7230955  Canine Ras-related protein Rab-18 (RAB18) ELISA Kit
 MBS1213527  Recombinant Parabacteroides distasonis Peptide chain release factor 1 (prfA)  MBS7603468  RELN Rabbit Polyclonal
Products associated with anti-REL antibodyPathways associated with anti-REL antibody
 Reference Product  PubMed Publications
 RELA antibody  >750 publications with REL and RELA
 NFKBIA antibody  >236 publications with REL and NFKBIA
 NFKB2 antibody  >104 publications with REL and NFKB2
 CD40 antibody  >97 publications with REL and CD40
 NFKB1 antibody  >95 publications with REL and NFKB1
 FOXP3 antibody  >33 publications with REL and FOXP3
 NFKBIE antibody  >16 publications with REL and NFKBIE
 TBK1 antibody  >4 publications with REL and TBK1
 MAPK8 antibody  >3 publications with REL and MAPK8
 NFKBIB antibody  >3 publications with REL and NFKBIB
 Products by Pathway  Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Atypical NF-kappaB Pathway antibodies  Atypical NF-kappaB Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Leptin Signaling Pathway antibodies  Leptin Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
 Regulation Of Androgen Receptor Activity Pathway antibodies  Regulation Of Androgen Receptor Activity Pathway Diagram
 Signaling By The B Cell Receptor (BCR) Pathway antibodies  Signaling By The B Cell Receptor (BCR) Pathway Diagram
Diseases associated with anti-REL antibodyOrgans/Tissues associated with anti-REL antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >479 publications with REL and Necrosis
 Inflammation Antibodies  >354 publications with REL and Inflammation
 Cell Transformation, Neoplastic Antibodies  >176 publications with REL and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >113 publications with REL and Disease Models, Animal
 Nervous System Diseases Antibodies  >104 publications with REL and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >99 publications with REL and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >64 publications with REL and Adenocarcinoma
 Lung Diseases Antibodies  >63 publications with REL and Lung Diseases
 Neoplasms, Experimental Antibodies  >60 publications with REL and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >57 publications with REL and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1037 publications with REL and Blood
 Lung Antibodies  >139 publications with REL and Lung
 Brain Antibodies  >135 publications with REL and Brain
 Liver Antibodies  >134 publications with REL and Liver
 Kidney Antibodies  >95 publications with REL and Kidney
 Embryonic Tissue Antibodies  >85 publications with REL and Embryonic Tissue
 Thymus Antibodies  >78 publications with REL and Thymus
 Lymph Node Antibodies  >52 publications with REL and Lymph Node
 Intestine Antibodies  >48 publications with REL and Intestine
 Lymph Antibodies  >44 publications with REL and Lymph
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions