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anti-RELB antibody :: Rabbit RELB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241890
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RELB, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal (IgG) to Human RELB

 Product Synonym Names    Anti-RELB Antibody (Ser552) IHC-plus; RELB; REL-B; Transcription factor RelB; I-Rel; IREL; Human RELB
 Product Gene Name   

anti-RELB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604758
 3D Structure    ModBase 3D Structure for Q01201
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    peptide encompassing amino acid Ser 552 of human RelB
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human RelB.
 Immunogen Type    Synthetic peptide
 Immunogen    RELB antibody was raised against synthetic peptide from human RelB.
 Antigen Modification    Ser552
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 Preparation and Storage    +4 degree C or -20 degree C, Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-RELB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RELB antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-RELB antibody    IHC-P (10 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-RELB antibody    Anti-RELB antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-RELB antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-RELB antibody    Western blot of extracts from HUVEC, 293 and HeLa cells using RelB(Ab-573) antibody.
anti-RELB antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RELB. It may not necessarily be applicable to this product.
 NCBI GI #    35493878
 NCBI GeneID    5971
 NCBI Accession #    NP_006500.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006509.3 [Other Products]
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 UniProt Primary Accession #    Q01201 [Other Products]
 UniProt Secondary Accession #    Q6GTX7; Q9UEI7 [Other Products]
 UniProt Related Accession #    Q01201 [Other Products]
 Molecular Weight    62,134 Da
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 NCBI Official Full Name    transcription factor RelB
 NCBI Official Synonym Full Names    v-rel avian reticuloendotheliosis viral oncogene homolog B
 NCBI Official Symbol    RELB [Similar Products]
 NCBI Official Synonym Symbols   
IREL; I-REL; REL-B
[Similar Products]
 NCBI Protein Information    transcription factor RelB; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
 UniProt Protein Name    Transcription factor RelB
 UniProt Synonym Protein Names   
I-Rel
 Protein Family    Antitoxin
 UniProt Gene Name    RELB [Similar Products]
 UniProt Entry Name    RELB_HUMAN
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 UniProt Comments for RELB    RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleoplasm; cytoplasm; microtubule organizing center; cytosol

Molecular Function: protein binding; chromatin binding; transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; I-kappaB kinase/NF-kappaB cascade; antigen processing and presentation; response to cytokine stimulus; T-helper 1 cell differentiation; innate immune response; positive regulation of transcription from RNA polymerase II promoter; myeloid dendritic cell differentiation; circadian regulation of gene expression; negative regulation of transcription from RNA polymerase II promoter; inflammatory response
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 Research Articles on RELB    1. RelB-p52 dimers were found to directly bind to the IDO promoter, leading to IDO expression in MDSCs
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RELB antibodyPathways associated with anti-RELB antibody
 Reference Product  PubMed Publications
 NFKB2 antibody  >98 publications with RELB and NFKB2
 IKBKB antibody  >76 publications with RELB and IKBKB
 CHUK antibody  >32 publications with RELB and CHUK
 NFKB1 antibody  >32 publications with RELB and NFKB1
 BCL3 antibody  >8 publications with RELB and BCL3
 NFKBIA antibody  >7 publications with RELB and NFKBIA
 MAP3K14 antibody  >3 publications with RELB and MAP3K14
 JAK2 antibody  >2 publications with RELB and JAK2
 RAC1 antibody  >1 publications with RELB and RAC1
 Products by Pathway  Pathway Diagram
 Alternative NF-kappaB Pathway antibodies  Alternative NF-kappaB Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
Diseases associated with anti-RELB antibodyOrgans/Tissues associated with anti-RELB antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >199 publications with RELB and Necrosis
 Inflammation Antibodies  >146 publications with RELB and Inflammation
 Breast Neoplasms Antibodies  >32 publications with RELB and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >21 publications with RELB and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >19 publications with RELB and Cardiovascular Diseases
 Lung Diseases Antibodies  >18 publications with RELB and Lung Diseases
 Kidney Diseases Antibodies  >14 publications with RELB and Kidney Diseases
 Liver Diseases Antibodies  >14 publications with RELB and Liver Diseases
 Neoplasms, Experimental Antibodies  >12 publications with RELB and Neoplasms, Experimental
 Chromosome Aberrations Antibodies  >10 publications with RELB and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >288 publications with RELB and Blood
 Bone Marrow Antibodies  >73 publications with RELB and Bone Marrow
 Spleen Antibodies  >51 publications with RELB and Spleen
 Thymus Antibodies  >40 publications with RELB and Thymus
 Lung Antibodies  >37 publications with RELB and Lung
 Vascular Antibodies  >34 publications with RELB and Vascular
 Lymph Node Antibodies  >31 publications with RELB and Lymph Node
 Kidney Antibodies  >31 publications with RELB and Kidney
 Lymph Antibodies  >30 publications with RELB and Lymph
 Muscle Antibodies  >28 publications with RELB and Muscle
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