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anti-RGPD5 antibody :: Rabbit anti-Human RGPD5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150170
Western Blot (WB)
Unit / Price
0.02 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RGPD5, Polyclonal Antibody

★Popular Item★
 Also Known As   

RGPD5 Antibody

 Product Synonym Names    RGPD5; BS63; RGP5; BS-63; HEL161; RANBP2L1; RGP7; RGPD7; RGPD6; RANBP2L2; RGP6; Sperm membrane protein BS-63; RanBP2L1; RANBP2-like and GRIP domain containing 5
 Product Gene Name   

anti-RGPD5 antibody

[Similar Products]
 Antibody/Peptide Pairs    RGPD5 peptide (MBS151890) is used for blocking the activity of RGPD5 antibody (MBS150170)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 612710
 3D Structure    ModBase 3D Structure for Q99666
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    RGPD5 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    RGPD5 antibody was raised against a 23 amino acid synthetic peptide from near the center of human RGPD5.
 Buffer    RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    RGPD5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-RGPD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RGPD5 antibody

   RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
 Applications Tested/Suitable for anti-RGPD5 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-RGPD5 antibody    RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 mug/mL.
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 Western Blot (WB) of anti-RGPD5 antibody    Western blot analysis of RGPD5 in human thymus tissue lysate with RGPD5 antibody at 1 μg/mL in (A) the absence and (B) the presense of blocking peptide.
anti-RGPD5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RGPD5. It may not necessarily be applicable to this product.
 NCBI GI #    83267877
 NCBI GeneID    84220
 NCBI Accession #    NP_005045 [Other Products]
 NCBI GenBank Nucleotide #    NM_005054.2 [Other Products]
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 UniProt Primary Accession #    Q99666 [Other Products]
 UniProt Secondary Accession #    Q53QN2; Q53T03; Q59GM7; Q9H0B2 [Other Products]
 UniProt Related Accession #    Q99666 [Other Products]
 Molecular Weight    103,334 Da
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 NCBI Official Full Name    RANBP2-like and GRIP domain-containing protein 5/6 isoform 1
 NCBI Official Synonym Full Names    RANBP2-like and GRIP domain containing 5
 NCBI Official Symbol    RGPD5 [Similar Products]
 NCBI Official Synonym Symbols   
BS63; RGP5; BS-63; HEL161
[Similar Products]
 NCBI Protein Information    RANBP2-like and GRIP domain-containing protein 5/6; ranBP2L1; ranBP2-like 1; ranBP2-like 1/2; ran-binding protein 2-like 1; sperm membrane protein BS-63; epididymis luminal protein 161; ran-binding protein 2-like 1/2
 UniProt Protein Name    RANBP2-like and GRIP domain-containing protein 5/6
 UniProt Synonym Protein Names   
Ran-binding protein 2-like 1/2; RanBP2-like 1/2; RanBP2L1; RanBP2L2; Sperm membrane protein BS-63
 Protein Family    RANBP2-like and GRIP domain-containing protein
 UniProt Gene Name    RGPD5 [Similar Products]
 UniProt Synonym Gene Names    RANBP2L1; RGP5; RGP7; RGPD7; RanBP2-like 1/2; RanBP2L1; RanBP2L2 [Similar Products]
 UniProt Entry Name    RGPD5_HUMAN
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 NCBI Summary for RGPD5    RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RGPD5    RGPD5/6: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: cytoplasm

Biological Process: protein targeting to Golgi
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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