NP_064339.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,322 Da
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 3 isoform 1
NCBI Official Synonym Full Names
receptor-interacting serine-threonine kinase 3
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 3; RIP-3; RIP-like protein kinase 3; mRIP3; receptor interacting protein 3; receptor-interacting protein 3
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 3
UniProt Synonym Protein Names
RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3; mRIP3
UniProt Synonym Gene Names
UniProt Entry Name
RIPK3_MOUSE
UniProt Comments for RIP3
RIPK3: Promotes apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Binds TRAF2 and RIPK1 and is recruited to the TNFR-1 signaling complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, TKL; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); TKL group; RIPK family
Cellular Component: membrane; mitochondrion; cytoplasm; plasma membrane; intracellular; cytosol
Molecular Function: transferase activity; NF-kappaB-inducing kinase activity; protein serine/threonine kinase activity; identical protein binding; protein binding; transferase activity, transferring phosphorus-containing groups; protein complex binding; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: spleen development; I-kappaB kinase/NF-kappaB cascade; regulation of activated T cell proliferation; thymus development; viral reproduction; protein heterooligomerization; protein amino acid autophosphorylation; programmed cell death; T cell differentiation in the thymus; positive regulation of transferase activity; protein amino acid phosphorylation; lymph node development; activation of NF-kappaB transcription factor; regulation of T cell mediated cytotoxicity; regulation of adaptive immune response; regulation of interferon-gamma production; activation of protein kinase activity; T cell homeostasis; positive regulation of ligase activity; phosphorylation; protein homooligomerization; positive regulation of oxidoreductase activity
Research Articles on RIP3
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Products associated with anti-RIP3 antibody
Pathways associated with anti-RIP3 antibody
Diseases associated with anti-RIP3 antibody
Organs/Tissues associated with anti-RIP3 antibody
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