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anti-RBM15 antibody :: Rabbit RNA binding motif protein 15 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711265 anti-RBM15 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNA binding motif protein 15 (RBM15), Polyclonal Antibody

 Also Known As   

Rabbit anti-human RNA binding motif protein 15 polyclonal Antibody

 Product Synonym Names    RNA binding motif protein 15; RBM15; FLJ12479; FLJ21943; MGC119584; OTT; OTT1; SPEN
 Product Gene Name   

anti-RBM15 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606077
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human RBM15
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82348 / sc-82351
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RBM15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RBM15 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for RBM15. It may not necessarily be applicable to this product.
 NCBI GI #    119576844
 NCBI GeneID    64783
 NCBI Accession #    EAW56440.1 [Other Products]
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 UniProt Secondary Accession #    Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; A1A693 [Other Products]
 UniProt Related Accession #    Q96T37 [Other Products]
 Molecular Weight    99,701 Da [Similar Products]
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 NCBI Official Full Name    RNA binding motif protein 15, isoform CRA_c
 NCBI Official Synonym Full Names    RNA binding motif protein 15
 NCBI Official Symbol    RBM15 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    putative RNA-binding protein 15; one twenty-two; one twenty two protein; one-twenty two protein 1; RNA-binding motif protein 15
 UniProt Protein Name    Putative RNA-binding protein 15
 UniProt Synonym Protein Names   
One-twenty two protein 1; RNA-binding motif protein 15
 Protein Family    Putative RNA-binding protein
 UniProt Gene Name    RBM15 [Similar Products]
 UniProt Synonym Gene Names    OTT; OTT1 [Similar Products]
 UniProt Entry Name    RBM15_HUMAN
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 NCBI Summary for RBM15    Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]
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 UniProt Comments for RBM15    RBM15: May be implicated in HOX gene regulation. A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia. Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains encoded by each gene and is the candidate oncogene. Belongs to the RRM Spen family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; Oncoprotein; RNA-binding

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: nucleoplasm; nuclear membrane

Molecular Function: protein binding; nucleotide binding

Biological Process: patterning of blood vessels; spleen development; negative regulation of myeloid cell differentiation; viral reproduction; negative regulation of transcription, DNA-dependent; activation of Notch receptor target transcription factor
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 Research Articles on RBM15    1. RBM15 does indeed play a critical role in the survival of chronic myelogenous leukemia (CML) cells, which may have potential application in designing molecular therapies for CML treatment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-RBM15 antibodyOrgans/Tissues associated with anti-RBM15 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with RBM15 and Breast Neoplasms
 Fibrosis Antibodies  >1 publications with RBM15 and Fibrosis
 Anemia Antibodies  >1 publications with RBM15 and Anemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with RBM15 and Blood
 Muscle Antibodies  >1 publications with RBM15 and Muscle
 Placenta Antibodies  >1 publications with RBM15 and Placenta
 Brain Antibodies  >1 publications with RBM15 and Brain
 Embryonic Tissue Antibodies  >1 publications with RBM15 and Embryonic Tissue
 Testis Antibodies  >1 publications with RBM15 and Testis
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