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anti-RPAP2 antibody :: Rabbit RNA polymerase II associated protein 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711590 anti-RPAP2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNA polymerase II associated protein 2 (RPAP2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human RNA polymerase II associated protein 2 polyclonal Antibody

 Product Synonym Names    RNA polymerase II associated protein 2; RPAP2; C1orf82; FLJ13150
 Product Gene Name   

anti-RPAP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611476
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human RPAP2
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RPAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RPAP2 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for RPAP2. It may not necessarily be applicable to this product.
 NCBI GI #    24659229
 NCBI GeneID    79871
 NCBI Accession #    AAH39014.1 [Other Products]
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 UniProt Secondary Accession #    Q49AS7; Q9H8Y2; C9JKB5 [Other Products]
 UniProt Related Accession #    Q8IXW5 [Other Products]
 Molecular Weight    66,473 Da [Similar Products]
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 NCBI Official Full Name    RNA polymerase II associated protein 2
 NCBI Official Synonym Full Names    RNA polymerase II associated protein 2
 NCBI Official Symbol    RPAP2 [Similar Products]
 NCBI Official Synonym Symbols   
C1orf82
[Similar Products]
 NCBI Protein Information    putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; RNA polymerase II-associated protein 2
 UniProt Protein Name    Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
 UniProt Synonym Protein Names   
RNA polymerase II-associated protein 2
 Protein Family    RNA polymerase II subunit B1 CTD phosphatase
 UniProt Gene Name    RPAP2 [Similar Products]
 UniProt Synonym Gene Names    C1orf82 [Similar Products]
 UniProt Entry Name    RPAP2_HUMAN
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 UniProt Comments for RPAP2    RPAP2: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. Belongs to the RPAP2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: cytoplasm; nucleolus; DNA-directed RNA polymerase II, holoenzyme; nucleus

Molecular Function: metal ion binding; CTD phosphatase activity

Biological Process: snRNA transcription
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 Research Articles on RPAP2    1. During transcription of snRNA genes, Ser7 phosphorylation facilitates recruitment of RPAP2, which in turn both recruits Integrator and dephosphorylates Ser5.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RPAP2 antibodyOrgans/Tissues associated with anti-RPAP2 antibody
 Reference Product  PubMed Publications
 RPAP1 antibody  >1 publications with RPAP2 and RPAP1
 GPN1 antibody  >1 publications with RPAP2 and GPN1
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with RPAP2 and Lung
 Blood Antibodies  >1 publications with RPAP2 and Blood
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