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anti-rtcB antibody :: Rabbit RNA-splicing ligase RtcB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489496 anti-rtcB antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNA-splicing ligase RtcB, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-Escherichia coli(strain K12)RNA-splicing ligase RtcB polyclonal Antibody, FITC

 Product Synonym Names    yhgL; b3421; JW3384
 Product Gene Name   

anti-rtcB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P46850
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Escherichia coli
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    FITC
 Immunogen    Recombinant Escherichia coli RNA-splicing ligase RtcB protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-rtcB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-rtcB antibody

   RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester.
 Applications Tested/Suitable for anti-rtcB antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for rtcB. It may not necessarily be applicable to this product.
 NCBI GI #    16131295
 NCBI GeneID    947929
 NCBI Accession #    NP_417879.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_000913.3 [Other Products]
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 UniProt Primary Accession #    P46850 [Other Products]
 UniProt Secondary Accession #    P76690; Q2M785 [Other Products]
 Molecular Weight    45,222 Da
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 NCBI Official Full Name    RNA-splicing ligase
 NCBI Official Symbol    rtcB [Similar Products]
 NCBI Official Synonym Symbols   
ECK3407; JW3384; yhgL
[Similar Products]
 NCBI Protein Information    RNA-splicing ligase
 UniProt Protein Name    RNA-splicing ligase RtcB
 Protein Family    RNA-splicing ligase
 UniProt Gene Name    rtcB [Similar Products]
 UniProt Synonym Gene Names    yhgL [Similar Products]
 UniProt Entry Name    RTCB_ECOLI
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 NCBI Summary for rtcB    RtcB has similarity to proteins found in Eucarya, Bacteria, and Archaea . [More information is available at EcoCyc: G7751].
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 UniProt Comments for rtcB    RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester, a step that requires GTP (PubMed:21224389, PubMed:22730297). Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-PO4 (or cyclic-PO4) and 5'-OH ends that cannot be sealed by classical DNA ligases (PubMed:24218597).
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 Research Articles on rtcB    1. Data show that RtcB seals broken RNAs with 3'-phosphate and 5'-OH ends.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-rtcB antibody
 Reference Product  PubMed Publications
 rtcA antibody  >7 publications with rtcB and rtcA
 folD antibody  >4 publications with rtcB and folD
 rtcR antibody  >2 publications with rtcB and rtcR
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