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anti-RNASE3 antibody :: Rabbit anti-Human RNASE3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS820633
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNASE3, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-RNASE3 Antibody

 Product Synonym Names    ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
 Product Gene Name   

anti-RNASE3 antibody

[Similar Products]
 Antibody/Peptide Pairs    RNASE3 peptide (MBS823676) is used for blocking the activity of RNASE3 antibody (MBS820633)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    131398
 3D Structure    ModBase 3D Structure for P12724
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes endogenous levels of RNASE3 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RNASE3. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-RNASE3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-RNASE3 antibody

   Rabbit polyclonal antibody to RNASE3
 Applications Tested/Suitable for anti-RNASE3 antibody   

Western Blot (WB)

 Application Notes for anti-RNASE3 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-RNASE3 antibody    Western blot analysis of RNASE3 expression in NCIH460 (A), HeLa (B) whole cell lysates.
anti-RNASE3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RNASE3. It may not necessarily be applicable to this product.
 NCBI GI #    45243507
 NCBI GeneID    6037
 NCBI Accession #    NP_002926.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002935.2 [Other Products]
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 UniProt Primary Accession #    P12724 [Other Products]
 UniProt Secondary Accession #    Q4VBC1; Q8WTP7; Q8WZ62; Q9GZN9 [Other Products]
 UniProt Related Accession #    P12724 [Other Products]
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 NCBI Official Full Name    eosinophil cationic protein
 NCBI Official Synonym Full Names    ribonuclease, RNase A family, 3
 NCBI Official Symbol    RNASE3 [Similar Products]
 NCBI Official Synonym Symbols   
ECP; RNS3
[Similar Products]
 NCBI Protein Information    eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease
 UniProt Protein Name    Eosinophil cationic protein
 UniProt Synonym Protein Names   
Ribonuclease 3; RNase 3
 Protein Family    Eosinophil cationic protein
 UniProt Gene Name    RNASE3 [Similar Products]
 UniProt Synonym Gene Names    ECP; RNS3; ECP; RNase 3 [Similar Products]
 UniProt Entry Name    ECP_HUMAN
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 NCBI Summary for RNASE3    The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
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 UniProt Comments for RNASE3    RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family.

Protein type: EC 3.1.27.-; Secreted, signal peptide; Ribonuclease; Secreted

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: nucleic acid binding; endonuclease activity; ribonuclease activity

Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response
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 Research Articles on RNASE3    1. The antimicrobial protein, Rnase 3, contributes to the host immune response against mycobacteria.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RNASE3 antibodyPathways associated with anti-RNASE3 antibody
 Reference Product  PubMed Publications
 RNASE2 antibody  >5 publications with RNASE3 and RNASE2
 MPO antibody  >5 publications with RNASE3 and MPO
 EPX antibody  >4 publications with RNASE3 and EPX
 IL5 antibody  >1 publications with RNASE3 and IL5
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
Diseases associated with anti-RNASE3 antibodyOrgans/Tissues associated with anti-RNASE3 antibody
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >73 publications with RNASE3 and Hypersensitivity
 Respiratory Tract Diseases Antibodies  >65 publications with RNASE3 and Respiratory Tract Diseases
 Respiratory Hypersensitivity Antibodies  >58 publications with RNASE3 and Respiratory Hypersensitivity
 Asthma Antibodies  >56 publications with RNASE3 and Asthma
 Lung Diseases Antibodies  >49 publications with RNASE3 and Lung Diseases
 Lung Diseases, Obstructive Antibodies  >47 publications with RNASE3 and Lung Diseases, Obstructive
 Inflammation Antibodies  >43 publications with RNASE3 and Inflammation
 Rhinitis Antibodies  >21 publications with RNASE3 and Rhinitis
 Eosinophilia Antibodies  >18 publications with RNASE3 and Eosinophilia
 Rhinitis, Allergic, Seasonal Antibodies  >13 publications with RNASE3 and Rhinitis, Allergic, Seasonal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >86 publications with RNASE3 and Blood
 Eye Antibodies  >2 publications with RNASE3 and Eye
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