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anti-RND2 antibody :: Rabbit RND2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8203296
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RND2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-RND2 Antibody

 Product Synonym Names    ARHN; RHO7; Rho-related GTP-binding protein RhoN; Rho family GTPase 2; Rho-related GTP-binding protein Rho7; Rnd2
 Product Gene Name   

anti-RND2 antibody

[Similar Products]
 Antibody/Peptide Pairs    RND2 peptide (MBS8239438) is used for blocking the activity of RND2 antibody (MBS8203296)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601555
 3D Structure    ModBase 3D Structure for P52198
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Specificity    Recognizes endogenous levels of RND2 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RND2. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-RND2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RND2 antibody

   Rabbit polyclonal antibody to RND2
 Applications Tested/Suitable for anti-RND2 antibody   

Western Blot (WB)

 Application Notes for anti-RND2 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-RND2 antibody    Western blot analysis of RND2 expression in HEK293T (A), NS-1 (B), PC12 (C) whole cell lysates.
anti-RND2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RND2. It may not necessarily be applicable to this product.
 NCBI GI #    4885581
 NCBI GeneID    8153
 NCBI Accession #    NP_005431.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005440.4 [Other Products]
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 UniProt Primary Accession #    P52198 [Other Products]
 UniProt Secondary Accession #    O00690; O00734; Q5U0P6; Q99535; A8K2D4 [Other Products]
 UniProt Related Accession #    P52198 [Other Products]
 Molecular Weight    25,369 Da
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 NCBI Official Full Name    rho-related GTP-binding protein RhoN
 NCBI Official Synonym Full Names    Rho family GTPase 2
 NCBI Official Symbol    RND2 [Similar Products]
 NCBI Official Synonym Symbols   
ARHN; RHO7; RhoN
[Similar Products]
 NCBI Protein Information    rho-related GTP-binding protein RhoN
 UniProt Protein Name    Rho-related GTP-binding protein RhoN
 UniProt Synonym Protein Names   
Rho family GTPase 2; Rho-related GTP-binding protein Rho7; Rnd2
 Protein Family    Rho-related GTP-binding protein
 UniProt Gene Name    RND2 [Similar Products]
 UniProt Synonym Gene Names    ARHN; RHO7 [Similar Products]
 UniProt Entry Name    RND2_HUMAN
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 NCBI Summary for RND2    This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RND2    RND2: May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric; G protein; G protein, monomeric, Rho

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: early endosome; acrosomal membrane

Molecular Function: GTPase activity; protein binding; GTP binding; protein N-terminus binding

Biological Process: metabolic process; small GTPase mediated signal transduction; signal transduction; positive regulation of collateral sprouting
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 Research Articles on RND2    1. Rnd2 regulates neurite outgrowth by functioning as the RhoA activator through Pragmin, in contrast to Rnd1 and Rnd3 inhibiting RhoA signaling
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RND2 antibodyDiseases associated with anti-RND2 antibody
 Reference Product  PubMed Publications
 ARHGAP35 antibody  >2 publications with RND2 and ARHGAP35
 SEMA3E antibody  >2 publications with RND2 and SEMA3E
 PLXND1 antibody  >2 publications with RND2 and PLXND1
 RRAS antibody  >2 publications with RND2 and RRAS
 PLXNB1 antibody  >1 publications with RND2 and PLXNB1
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with RND2 and Nervous System Diseases
 Breast Neoplasms Antibodies  >1 publications with RND2 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with RND2 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >1 publications with RND2 and Disease Models, Animal
Organs/Tissues associated with anti-RND2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with RND2 and Brain
 Embryonic Tissue Antibodies  >5 publications with RND2 and Embryonic Tissue
 Testis Antibodies  >3 publications with RND2 and Testis
 Uterus Antibodies  >2 publications with RND2 and Uterus
 Liver Antibodies  >1 publications with RND2 and Liver
 Epididymis Antibodies  >1 publications with RND2 and Epididymis
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