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anti-RXFP3 antibody :: Rabbit anti-Human RXFP3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7043830
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RXFP3, Polyclonal Antibody

★Popular Item★
 Also Known As   

RXFP3 Antibody

 Product Synonym Names    Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor; RXFP3; RLN3R1; SALPR
 Product Gene Name   

anti-RXFP3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609445
 3D Structure    ModBase 3D Structure for Q9NSD7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Relaxin-3 receptor 1 protein (N-80AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47004 / sc-98725
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RXFP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RXFP3 antibody

   Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
 Applications Tested/Suitable for anti-RXFP3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-RXFP3 antibody    Western blot
All lanes: RXFP3 antibody at 3.68ug/ml
Lane 1: Jurkat whole cell lysate
Lane 2: HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa

anti-RXFP3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-RXFP3 antibody    Immunohistochemistry of paraffin-embedded human liver cancer MBS7043830 at dilution 1:100
anti-RXFP3 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-RXFP3 antibody    Immunohistochemistry of paraffin-embedded human pancreatic cancer MBS7043830 at dilution 1:100
anti-RXFP3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for RXFP3. It may not necessarily be applicable to this product.
 NCBI GI #    7706103
 NCBI GeneID    51289
 NCBI Accession #    NP_057652.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016568.3 [Other Products]
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 UniProt Primary Accession #    Q9NSD7 [Other Products]
 UniProt Secondary Accession #    Q14DA5 [Other Products]
 UniProt Related Accession #    Q9NSD7 [Other Products]
 Molecular Weight    51,124 Da
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 NCBI Official Full Name    relaxin-3 receptor 1
 NCBI Official Synonym Full Names    relaxin/insulin like family peptide receptor 3
 NCBI Official Symbol    RXFP3 [Similar Products]
 NCBI Official Synonym Symbols   
SALPR; RLN3R1; RXFPR3; GPCR135
[Similar Products]
 NCBI Protein Information    relaxin-3 receptor 1
 UniProt Protein Name    Relaxin-3 receptor 1
 UniProt Synonym Protein Names   
G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
 Protein Family    Relaxin-3 receptor
 UniProt Gene Name    RXFP3 [Similar Products]
 UniProt Synonym Gene Names    RLN3R1; SALPR; RLN3 receptor 1 [Similar Products]
 UniProt Entry Name    RL3R1_HUMAN
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 UniProt Comments for RXFP3    RLN3R1: Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5p15.1-p14

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide receptor activity, G-protein coupled

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); neuropeptide signaling pathway; positive regulation of cytokinesis
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 Research Articles on RXFP3    1. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-RXFP3 antibodyDiseases associated with anti-RXFP3 antibody
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Relaxin Receptors Pathway antibodies  Relaxin Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Disease Name  Pubmed Publications
 Memory Disorders Antibodies  >6 publications with RXFP3 and Memory Disorders
 Learning Disorders Antibodies  >5 publications with RXFP3 and Learning Disorders
 Fibrosis Antibodies  >5 publications with RXFP3 and Fibrosis
 Weight Gain Antibodies  >4 publications with RXFP3 and Weight Gain
 Vascular Diseases Antibodies  >3 publications with RXFP3 and Vascular Diseases
 Disease Models, Animal Antibodies  >3 publications with RXFP3 and Disease Models, Animal
 Uterine Neoplasms Antibodies  >2 publications with RXFP3 and Uterine Neoplasms
 Kidney Diseases Antibodies  >1 publications with RXFP3 and Kidney Diseases
 Infertility, Male Antibodies  >1 publications with RXFP3 and Infertility, Male
 Infertility, Female Antibodies  >1 publications with RXFP3 and Infertility, Female
Organs/Tissues associated with anti-RXFP3 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >62 publications with RXFP3 and Brain
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