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anti-Rab1b antibody :: Goat Rab1b Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS448132 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
0.3 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rab1b, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rab1b Polyclonal Antibody

 Product Synonym Names    RAB1, member RAS oncogene family; Anti-Rab1b; RAB1A; RAB1B; RAS-associated protein RAB1A; ras-related protein Rab-1B; ras-related protein Rab-1A; ras-related protein Rab-1B; YPT1 antibody
 Product Gene Name   

anti-Rab1b antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF092437 mRNA
 3D Structure    ModBase 3D Structure for Q9H0U4
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
 Species Reactivity    Human, Rat, Mouse, Canine, Monkey proteins
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 Specificity    Detects endogenous levels of Rab1b protein by Western blot in whole cell lysates and transfected cells with GFP-Rab1b cds.
 Purity/Purification    Epitope Affinity Purified
 Form/Format    Supplied as a 100 ul (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
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 Immunogen    Purified recombinant peptide derived from within residues 110 aa to the C-terminus of Rab1b produced in E Coli.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
The antibody solution should be gently mixed before use.
Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-Rab1b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Rab1b antibody

   Goat polyclonal antibody to Rab1b. Rab1b belongs to the small GTPase superfamily, Rab family. Rab1b together with Rab1a control vesicle traffic from the endoplasmic reticulum to the Golgi apparatus.
 Applications Tested/Suitable for anti-Rab1b antibody   

Western Blot (WB)

 Application Notes for anti-Rab1b antibody    WB: 1:500-1:5,000
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 Reactivity Chart of anti-Rab1b antibody    anti-Rab1b antibody Reactivity Chart image
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 Wester Blot (WB) of anti-Rab1b antibody    anti-Rab1b antibody Wester Blot (WB) image
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NCBI/Uniprot data below describe general gene information for Rab1b. It may not necessarily be applicable to this product.
 NCBI GI #    13569962
 NCBI GeneID    81876
 NCBI Accession #    NP_112243.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030981.2 [Other Products]
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 UniProt Primary Accession #    Q9H0U4 [Other Products]
 UniProt Secondary Accession #    A8K7S1 [Other Products]
 UniProt Related Accession #    Q9H0U4 [Other Products]
 Molecular Weight    22,171 Da
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 NCBI Official Full Name    ras-related protein Rab-1B
 NCBI Official Synonym Full Names    RAB1B, member RAS oncogene family
 NCBI Official Symbol    RAB1B [Similar Products]
 NCBI Protein Information    ras-related protein Rab-1B
 UniProt Protein Name    Ras-related protein Rab-1B
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB1B [Similar Products]
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 NCBI Summary for Rab1b    Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]
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 UniProt Comments for Rab1b    RAB1B: Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytosol; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; pre-autophagosomal structure membrane; transport vesicle

Molecular Function: GTP binding; protein binding

Biological Process: COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; post-translational protein modification; retrograde vesicle-mediated transport, Golgi to ER; virus assembly
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 Research Articles on Rab1b    1. Authors demonstrate that Rap1b expression is aberrantly increased in GC, resulting in the inhibition of autophagy and apoptosis of GC cells by the PI3K/Akt/mTOR pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Rab1b antibodyPathways associated with anti-Rab1b antibody
 Reference Product  PubMed Publications
 RAB1A antibody  >12 publications with Rab1b and RAB1A
 ARF1 antibody  >8 publications with Rab1b and ARF1
 LMAN1 antibody  >1 publications with Rab1b and LMAN1
 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPI-dependent Golgi-to-ER Retrograde Traffic Pathway antibodies  COPI-dependent Golgi-to-ER Retrograde Traffic Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Golgi Cisternae Pericentriolar Stack Reorganization Pathway antibodies  Golgi Cisternae Pericentriolar Stack Reorganization Pathway Diagram
 Golgi-to-ER Retrograde Transport Pathway antibodies  Golgi-to-ER Retrograde Transport Pathway Diagram
 Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway antibodies  Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway Diagram
Diseases associated with anti-Rab1b antibodyOrgans/Tissues associated with anti-Rab1b antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with Rab1b and Carcinoma
 Liver Neoplasms Antibodies  >2 publications with Rab1b and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with Rab1b and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with Rab1b and Liver Diseases
 Breast Neoplasms Antibodies  >2 publications with Rab1b and Breast Neoplasms
 Inflammation Antibodies  >2 publications with Rab1b and Inflammation
 Kidney Diseases Antibodies  >2 publications with Rab1b and Kidney Diseases
 Precancerous Conditions Antibodies  >1 publications with Rab1b and Precancerous Conditions
 Genital Diseases, Male Antibodies  >1 publications with Rab1b and Genital Diseases, Male
 Fibrosis Antibodies  >1 publications with Rab1b and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >7 publications with Rab1b and Kidney
 Liver Antibodies  >6 publications with Rab1b and Liver
 Brain Antibodies  >6 publications with Rab1b and Brain
 Blood Antibodies  >5 publications with Rab1b and Blood
 Nerve Antibodies  >5 publications with Rab1b and Nerve
 Lung Antibodies  >3 publications with Rab1b and Lung
 Eye Antibodies  >2 publications with Rab1b and Eye
 Bone Antibodies  >2 publications with Rab1b and Bone
 Uterus Antibodies  >1 publications with Rab1b and Uterus
 Testis Antibodies  >1 publications with Rab1b and Testis
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