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anti-Rab2 antibody :: Goat Rab2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS448028 (SPECIAL PROMOTIONAL PRICING for a limited time)
Reactivity Chart
Unit / Price
0.4 mg  /  $285 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rab2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rab2 Pan Polyclonal Antibody

 Product Synonym Names    Anti-Rab2; Ras-related protein Rab-2A; Ras-related protein Rab-2B antibody
 Product Gene Name   

anti-Rab2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 8; NC_000008.11 (60516910..60623644). Location: 8q12.1
 OMIM    179509
 3D Structure    ModBase 3D Structure for P61019
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
 Species Reactivity    Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
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 Specificity    Detects total levels of Rab2 protein in transfected cells with GFP-Rab2a and GFP-Rab2b by Western blot.
 Form/Format    Polyclonal antibody supplied as (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
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 Gene Identifier    ENSG00000104388
 Immunogen    Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
 Antigen    Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
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 Preparation and Storage    For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.
 Other Notes    Small volumes of anti-Rab2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Rab2 antibody

   RAB2, member RAS oncogene family

RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A has been shown to interact with GOLGA2.
 Applications Tested/Suitable for anti-Rab2 antibody   

Western Blot (WB)

 Application Notes for anti-Rab2 antibody    Western Blot: 1:250-1:2,000
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 Reactivity Chart of anti-Rab2 antibody    anti-Rab2 antibody Reactivity Chart image
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NCBI/Uniprot data below describe general gene information for Rab2. It may not necessarily be applicable to this product.
 NCBI GI #    3283897
 NCBI GeneID    5862
 NCBI Accession #    AAC25389.1 [Other Products]
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 UniProt Primary Accession #    P61019 [Other Products]
 UniProt Secondary Accession #    P08886; B2R5W8; B4DMQ5 [Other Products]
 UniProt Related Accession #    P61019 [Other Products]
 Molecular Weight    23,546 Da
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 NCBI Official Full Name    RAB2
 NCBI Official Synonym Full Names    RAB2A, member RAS oncogene family
 NCBI Official Symbol    RAB2A [Similar Products]
 NCBI Official Synonym Symbols   
LHX; RAB2
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-2A; small GTP binding protein RAB2A; RAB2, member RAS oncogene family
 UniProt Protein Name    Ras-related protein Rab-2A
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB2A [Similar Products]
 UniProt Synonym Gene Names    RAB2 [Similar Products]
 UniProt Entry Name    RAB2A_HUMAN
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 NCBI Summary for Rab2    The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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 UniProt Comments for Rab2    Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex.

Subunit structure: Interacts with PRKCI. Ref.10

Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor

Potential. Golgi apparatus membrane; Lipid-anchor

Potential. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Ref.11

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.
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 Research Articles on Rab2    1. The authors identified a specific interaction between the human small GTPase Rab2 and a Brucella spp. protein named RicA.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Rab2 antibodyDiseases associated with anti-Rab2 antibody
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Golgi Cisternae Pericentriolar Stack Reorganization Pathway antibodies  Golgi Cisternae Pericentriolar Stack Reorganization Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic Prophase Pathway antibodies  Mitotic Prophase Pathway Diagram
 Disease Name  Pubmed Publications
 Uterine Cervical Neoplasms Antibodies  >1 publications with Rab2 and Uterine Cervical Neoplasms
 Neoplasms Antibodies  >1 publications with Rab2 and Neoplasms
Organs/Tissues associated with anti-Rab2 antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with Rab2 and Skin
 Brain Antibodies  >2 publications with Rab2 and Brain
 Bone Antibodies  >1 publications with Rab2 and Bone
 Spleen Antibodies  >1 publications with Rab2 and Spleen
 Muscle Antibodies  >1 publications with Rab2 and Muscle
 Liver Antibodies  >1 publications with Rab2 and Liver
 Heart Antibodies  >1 publications with Rab2 and Heart
 Kidney Antibodies  >1 publications with Rab2 and Kidney
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