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anti-Rab8 antibody :: Rabbit anti-Human Rab8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS620263 anti-Rab8 antibody
Unit / Price
0.1 mL  /  $480 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rab8, Polyclonal Antibody

 Also Known As   

Rab8

 Product Synonym Names    Anti -Rab8
 Product Gene Name   

anti-Rab8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3L; NT_037436.3 (19860588..19864157, complement). Location: 76D2-76D3
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human Rab8. Species crossreactivity: mouse, rat, monkey.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied in 10mM sodium HEPES (pH 7.5), 150mM NaCl, 100ug/ml BSA and 50% glycerol.
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 Immunogen    Synthetic peptide corresponding to residues surrounding Met173 of human Rab8 protein (KLH-coupled).
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-Rab8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Rab8 antibody

   The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring (1). Studies show that Rab8 is localized to the trans Golgi network (TGN), basolateral membrane and vesicular structures where it helps regulate target protein transport between TGN and the basolateral membrane (1-3). Overexpression studies and mutation analysis of Rab8 and its associated Rab8GEF indicate additional roles in actin and microtubule remodeling during polarized membrane transport and membrane protrusion formation (4-6). Rab8 associates with myosin Vb and is required for translocation of GLUT4 following insulin stimulation in muscle (7,8). Control of target protein vesicle transport by Rab8 also regulates MT1-MMP activity during extracellular matrix formation and JRAB/MICAL-L2 at tight junction formation (9,10).
 Product Categories/Family for anti-Rab8 antibody    Antibodies; Abs to GTPase, Rab, Ras, Rho Proteins
 Applications Tested/Suitable for anti-Rab8 antibody   

Western Blot (WB)

 Application Notes for anti-Rab8 antibody    Suitable for use in Western Blot.
Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1%
Tween-20 at 4 degree C with gentle shaking, overnight.
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NCBI/Uniprot data below describe general gene information for Rab8. It may not necessarily be applicable to this product.
 NCBI GI #    17737663
 NCBI GeneID    40168
 NCBI Accession #    NP_524172.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_079448.2 [Other Products]
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 NCBI Official Full Name    Rab-protein 8
 NCBI Official Synonym Full Names    Rab-protein 8
 NCBI Official Symbol    Rab8 [Similar Products]
 NCBI Official Synonym Symbols   
AAF49101; CG8287; Dm Rab8; dm-Rab8; DmelCG8287; DmRab8; DRab8; DRAB8; Rab-r8; rab8
[Similar Products]
 NCBI Protein Information    CG8287 gene product from transcript CG8287-RA; Rab-protein 8; CG8287-PA; Rab8-PA
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-Rab8 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Rab8 and Bone
 Connective Tissue Antibodies  >4 publications with Rab8 and Connective Tissue
 Heart Antibodies  >3 publications with Rab8 and Heart
 Muscle Antibodies  >3 publications with Rab8 and Muscle
 Brain Antibodies  >3 publications with Rab8 and Brain
 Vascular Antibodies  >2 publications with Rab8 and Vascular
 Embryonic Tissue Antibodies  >2 publications with Rab8 and Embryonic Tissue
 Ear Antibodies  >1 publications with Rab8 and Ear
 Kidney Antibodies  >1 publications with Rab8 and Kidney
 Umbilical Cord Antibodies  >1 publications with Rab8 and Umbilical Cord
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