Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow RAB5A rightarrow Polyclonal RAB5A  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • NDUFS1 Antibody
 • Interleukin 18 (IL18) ELISA Kit
 • ACTN2 Antibody
 • DCTN4 Antibody
 • CD47 molecule ELISA Kit
 • SNX26-TCGAP Antibody
 • Envelope glycoprotein (GP) Recombinant Protein
 • Glycophorin A (GYPA) Antibody
 • Lactoferrin (LF) ELISA Kit
 • CA2 ELISA Kit
 • Adipocyte fatty acid-binding protein, a-FABP ELISA Kit
 • Cyclophilin B (CYPB) ELISA Kit
 • Acidic Hair Keratin, K35 Antibody
 • ACE2 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-RAB5A antibody :: Rabbit anti-Human, Mouse Ras-related protein Rab-5A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1499177
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ras-related protein Rab-5A (RAB5A), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Ras-related protein Rab-5A polyclonal Antibody(RAB5A)

 Product Synonym Names    RAB5A; RAB5
 Product Gene Name   

anti-RAB5A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    179512
 3D Structure    ModBase 3D Structure for P20339
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    Antigen Affinity Purified
Section Bar
 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Ras-related protein Rab-5A protein(1-215aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28570 / sc-130010 / sc-309 / sc-26566
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RAB5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-RAB5A antibody

   The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension.
 Applications Tested/Suitable for anti-RAB5A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-RAB5A antibody    Recommended dilution: WB:1:500-5000
IHC:1:20-1:200
Section Bar
 Western Blot (WB) of anti-RAB5A antibody    All lanes: Ras-related protein Rab-5A antibody at 5ug/ml
Lane 1:mouse brain tissue
Lane 2:HL-60 whole cell lysate
Lane 3:Hela whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 24,23 kDa
Observed band size: 24 kDa

anti-RAB5A antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-RAB5A antibody    Immunohistochemistry of paraffin-embedded human rectal cancer using MBS1499177 at dilution 1:100
anti-RAB5A antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RAB5A. It may not necessarily be applicable to this product.
 NCBI GI #    635574573
 NCBI GeneID    5868
 NCBI Accession #    NP_001278977.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001292048.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P20339 [Other Products]
 UniProt Secondary Accession #    Q6FI44; B4DJA5 [Other Products]
 UniProt Related Accession #    P20339 [Other Products]
 Molecular Weight    22,178 Da
Table BarTOPTable Bar
 NCBI Official Full Name    ras-related protein Rab-5A isoform 2
 NCBI Official Synonym Full Names    RAB5A, member RAS oncogene family
 NCBI Official Symbol    RAB5A [Similar Products]
 NCBI Official Synonym Symbols   
RAB5
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-5A
 UniProt Protein Name    Ras-related protein Rab-5A
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB5A [Similar Products]
 UniProt Synonym Gene Names    RAB5 [Similar Products]
 UniProt Entry Name    RAB5A_HUMAN
Section Bar
 UniProt Comments for RAB5A    RAB5A: Required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, RABEP1, SUN2, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3. Interacts with PIK3CB. Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; G protein, monomeric; Motility/polarity/chemotaxis; G protein

Chromosomal Location of Human Ortholog: 3p24-p22

Cellular Component: actin cytoskeleton; axon; cell soma; cytoplasm; cytosol; dendrite; early endosome; endocytic vesicle; endosome; endosome membrane; lipid raft; melanosome; nerve terminal; phagocytic vesicle; plasma membrane; ruffle; synaptic vesicle; terminal button

Molecular Function: GDP binding; GTP binding; GTPase activity; protein binding

Biological Process: blood coagulation; early endosome to late endosome transport; endocytosis; positive regulation of exocytosis; protein transport; regulation of endocytosis; regulation of endosome size; regulation of filopodium formation; small GTPase mediated signal transduction
Table BarTOPTable Bar
 Research Articles on RAB5A    1. findings suggest that Rab5 expression is required to maintain characteristics associated with cell transformation
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-RAB5A antibodyPathways associated with anti-RAB5A antibody
 Reference Product  PubMed Publications
 EEA1 antibody  >13 publications with RAB5A and EEA1
 APPL1 antibody  >4 publications with RAB5A and APPL1
 RABGEF1 antibody  >2 publications with RAB5A and RABGEF1
 ALS2 antibody  >1 publications with RAB5A and ALS2
 ZFYVE20 antibody  >1 publications with RAB5A and ZFYVE20
 RABEP1 antibody  >1 publications with RAB5A and RABEP1
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Diseases associated with anti-RAB5A antibodyOrgans/Tissues associated with anti-RAB5A antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >10 publications with RAB5A and Neoplasm Metastasis
 Inflammation Antibodies  >9 publications with RAB5A and Inflammation
 Carcinoma, Hepatocellular Antibodies  >5 publications with RAB5A and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >4 publications with RAB5A and Liver Diseases
 Kidney Diseases Antibodies  >4 publications with RAB5A and Kidney Diseases
 Brain Diseases Antibodies  >3 publications with RAB5A and Brain Diseases
 Uterine Cervical Neoplasms Antibodies  >2 publications with RAB5A and Uterine Cervical Neoplasms
 Fibrosis Antibodies  >2 publications with RAB5A and Fibrosis
 Atherosclerosis Antibodies  >2 publications with RAB5A and Atherosclerosis
 Weight Loss Antibodies  >2 publications with RAB5A and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >17 publications with RAB5A and Kidney
 Brain Antibodies  >17 publications with RAB5A and Brain
 Lung Antibodies  >15 publications with RAB5A and Lung
 Blood Antibodies  >14 publications with RAB5A and Blood
 Liver Antibodies  >10 publications with RAB5A and Liver
 Nerve Antibodies  >9 publications with RAB5A and Nerve
 Vascular Antibodies  >9 publications with RAB5A and Vascular
 Heart Antibodies  >8 publications with RAB5A and Heart
 Muscle Antibodies  >6 publications with RAB5A and Muscle
 Skin Antibodies  >5 publications with RAB5A and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions