NP_000557.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,795 Da
NCBI Official Full Name
high affinity immunoglobulin gamma Fc receptor I
NCBI Official Synonym Full Names
Fc fragment of IgG receptor Ia
NCBI Protein Information
high affinity immunoglobulin gamma Fc receptor I
UniProt Protein Name
High affinity immunoglobulin gamma Fc receptor I
UniProt Synonym Protein Names
Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64
UniProt Synonym Gene Names
NCBI Summary for FcgRI
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
UniProt Comments for FcgRI
FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: early endosome membrane; integral component of membrane; plasma membrane
Molecular Function: IgG binding; protein binding; receptor signaling protein activity
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; immune response; phagocytosis, engulfment; receptor-mediated endocytosis; regulation of immune response; signal transduction
Research Articles on FcgRI
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Disclaimer
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Pathways associated with anti-FcgRI antibody
Diseases associated with anti-FcgRI antibody
Organs/Tissues associated with anti-FcgRI antibody
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