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anti-RYK antibody :: Rabbit anti-Mouse Related To Receptor Tyrosine Kinase (RYK) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2015810 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $195 +1 FREE 8GB USB
0.1 mg  /  $250 +1 FREE 8GB USB
0.2 mg  /  $380 +1 FREE 8GB USB
1 mg  /  $905 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Related To Receptor Tyrosine Kinase (RYK), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Related To Receptor Tyrosine Kinase (RYK)

 Product Gene Name   

anti-RYK antibody

[Similar Products]
 Matching Pairs    Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
Antigen: Related To Receptor Tyrosine Kinase (RYK) (MBS2018498)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
APC-CY7 Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083645)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
PE Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083646)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
APC-CY7 Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083647)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
Cy3 Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083648)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
FITC Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083649)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
HRP Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2083650)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2015810)
Biotin Conjugated Antibody: Related To Receptor Tyrosine Kinase (RYK) (MBS2096934)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q01887
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against RYK. It has been selected for its ability to recognize RYK in immunohistochemical staining andwestern blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography.
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant RYK (Thr287-IIe527) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2083647
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-RYK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-RYK antibody   

WB; IHC; ICC; IP.

 Application Notes for anti-RYK antibody    Western blotting: 0.5-5 ug/ml
Immunocytochemistry in formalin fixed cells: 5-20 ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20 ug/ml
Immunohistochemistry in paraffin section: 5-20 ug/ml
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-RYK antibody    (Figure. Western Blot; Sample: Human Jurkat Cells.)
anti-RYK antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-RYK antibody    (Figure. Western Blot;.Sample: Recombinant RYK, Mouse.)
anti-RYK antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-RYK antibody    (Figure.DAB staining on IHC-P. Samples: Mouse Tissue)
anti-RYK antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for RYK. It may not necessarily be applicable to this product.
 NCBI GI #    110681702
 NCBI GeneID    20187
 NCBI Accession #    NP_001036072.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042607.1 [Other Products]
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 UniProt Primary Accession #    Q01887 [Other Products]
 UniProt Secondary Accession #    Q61890 [Other Products]
 UniProt Related Accession #    Q01887 [Other Products]
 Molecular Weight    66,285 Da
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 NCBI Official Full Name    tyrosine-protein kinase RYK isoform 2
 NCBI Official Synonym Full Names    receptor-like tyrosine kinase
 NCBI Official Symbol    Ryk [Similar Products]
 NCBI Official Synonym Symbols   
Vik; ERK-3; AW536699
[Similar Products]
 NCBI Protein Information    tyrosine-protein kinase RYK
 UniProt Protein Name    Tyrosine-protein kinase RYK
 UniProt Synonym Protein Names   
Kinase VIK; Met-related kinase; NYK-R
 Protein Family    Tyrosine-protein kinase
 UniProt Gene Name    Ryk [Similar Products]
 UniProt Synonym Gene Names    Mrk [Similar Products]
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 UniProt Comments for RYK    RYK: a receptor tyrosine kinase of the Ryk family. Associates with, and may modulate the signaling of, EphB2 and EphB3. Expressed in nestin-positive progenitor cells and neurons, some oligodendrocytes, O-2A progenitor cells, and type-2 astrocytes in developing CNS.

Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); Ryk family; TK group

Chromosomal Location of Human Ortholog: 9 F1|9 54.72 cM

Cellular Component: cytoplasm; integral component of membrane; membrane; nucleus; plasma membrane

Molecular Function: ATP binding; frizzled binding; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; transferase activity; transmembrane receptor activity; transmembrane receptor protein tyrosine kinase activity; Wnt-activated receptor activity; Wnt-protein binding

Biological Process: axon guidance; axonogenesis; chemorepulsion of dopaminergic neuron axon; commissural neuron axon guidance; corpus callosum development; midbrain dopaminergic neuron differentiation; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neuron differentiation; neuron projection development; phosphorylation; planar cell polarity pathway involved in axon guidance; positive regulation of MAPK cascade; protein amino acid phosphorylation; skeletal morphogenesis; Wnt signaling pathway
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 Research Articles on RYK    1. reveal a novel function of Ryk signaling in controlling motor cortex remapping after spinal cord injury in adulthood.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-RYK antibodyOrgans/Tissues associated with anti-RYK antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >33 publications with RYK and Neoplasms
 Cardiovascular Diseases Antibodies  >14 publications with RYK and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >12 publications with RYK and Nervous System Diseases
 Carcinoma Antibodies  >9 publications with RYK and Carcinoma
 Urinary Bladder Neoplasms Antibodies  >9 publications with RYK and Urinary Bladder Neoplasms
 Kidney Diseases Antibodies  >6 publications with RYK and Kidney Diseases
 Adenocarcinoma Antibodies  >5 publications with RYK and Adenocarcinoma
 Inflammation Antibodies  >4 publications with RYK and Inflammation
 Cell Transformation, Neoplastic Antibodies  >4 publications with RYK and Cell Transformation, Neoplastic
 Craniofacial Abnormalities Antibodies  >4 publications with RYK and Craniofacial Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >41 publications with RYK and Other
 Brain Antibodies  >32 publications with RYK and Brain
 Embryonic Tissue Antibodies  >27 publications with RYK and Embryonic Tissue
 Lung Antibodies  >15 publications with RYK and Lung
 Bone Antibodies  >11 publications with RYK and Bone
 Kidney Antibodies  >10 publications with RYK and Kidney
 Bladder Antibodies  >9 publications with RYK and Bladder
 Muscle Antibodies  >8 publications with RYK and Muscle
 Liver Antibodies  >8 publications with RYK and Liver
 Eye Antibodies  >6 publications with RYK and Eye
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