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anti-RPA3 antibody :: Rabbit anti-Human Replication protein A 14 kDa subunit Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490173
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Replication protein A 14 kDa subunit (RPA3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Replication protein A 14 kDa subunit polyclonal Antibody

 Product Synonym Names    Replication factor A protein 3; RPA3; REPA3; RPA14
 Product Gene Name   

anti-RPA3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    179837
 3D Structure    ModBase 3D Structure for P35244
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Replication protein A 14 kDa subunit protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30409 / sc-46623 / sc-46507 / sc-30411
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RPA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RPA3 antibody

   Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
 Applications Tested/Suitable for anti-RPA3 antibody   

ELISA (EIA), Western Blot (WB)

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 Western Blot (WB) of anti-RPA3 antibody    Western blot
All lanes: Replication protein A 14 kDa
subunit antibody at 2ug/ml
Lane 1: LO2 whole cell lysate
Lane 2:HepG2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 14kDa
Observed band size: 14kDa

anti-RPA3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RPA3. It may not necessarily be applicable to this product.
 NCBI GI #    4506587
 NCBI GeneID    6119
 NCBI Accession #    NP_002938.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002947.4 [Other Products]
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 UniProt Primary Accession #    P35244 [Other Products]
 UniProt Secondary Accession #    Q549U6 [Other Products]
 UniProt Related Accession #    P35244 [Other Products]
 Molecular Weight    13,569 Da [Similar Products]
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 NCBI Official Full Name    replication protein A 14 kDa subunit
 NCBI Official Synonym Full Names    replication protein A3
 NCBI Official Symbol    RPA3 [Similar Products]
 NCBI Official Synonym Symbols   
REPA3; RP-A p14
[Similar Products]
 NCBI Protein Information    replication protein A 14 kDa subunit
 UniProt Protein Name    Replication protein A 14 kDa subunit
 UniProt Synonym Protein Names   
Replication factor A protein 3; RF-A protein 3
 Protein Family    Replication protein
 UniProt Gene Name    RPA3 [Similar Products]
 UniProt Synonym Gene Names    REPA3; RPA14; RP-A p14; RF-A protein 3 [Similar Products]
 UniProt Entry Name    RFA3_HUMAN
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 UniProt Comments for RPA3    RPA3: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: DNA replication factor A complex; nucleoplasm

Molecular Function: damaged DNA binding; protein binding; single-stranded DNA binding

Biological Process: base-excision repair; bypass DNA synthesis; DNA damage response, detection of DNA damage; DNA repair; DNA replication; DNA strand elongation during DNA replication; double-strand break repair; double-strand break repair via homologous recombination; error-prone postreplication DNA repair; G1/S transition of mitotic cell cycle; mismatch repair; mitotic cell cycle; nucleotide-excision repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair, DNA incision; regulation of cell proliferation; regulation of mitotic cell cycle; telomere maintenance; telomere maintenance via recombination; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair
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 Research Articles on RPA3    1. The allele "T" of rs6947203 in the RPA3 gene acts as a protective allele in glioma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RPA3 antibodyPathways associated with anti-RPA3 antibody
 Reference Product  PubMed Publications
 RPA2 antibody  >38 publications with RPA3 and RPA2
 RPA1 antibody  >28 publications with RPA3 and RPA1
 RPA4 antibody  >6 publications with RPA3 and RPA4
 PCNA antibody  >3 publications with RPA3 and PCNA
 RAD51 antibody  >1 publications with RPA3 and RAD51
 POLD1 antibody  >1 publications with RPA3 and POLD1
 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chromosome Maintenance Pathway antibodies  Chromosome Maintenance Pathway Diagram
 DNA Damage Bypass Pathway antibodies  DNA Damage Bypass Pathway Diagram
Diseases associated with anti-RPA3 antibodyOrgans/Tissues associated with anti-RPA3 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with RPA3 and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with RPA3 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with RPA3 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >1 publications with RPA3 and Ovarian Neoplasms
 Precancerous Conditions Antibodies  >1 publications with RPA3 and Precancerous Conditions
 Breast Neoplasms Antibodies  >1 publications with RPA3 and Breast Neoplasms
 Weight Loss Antibodies  >1 publications with RPA3 and Weight Loss
 Kidney Diseases Antibodies  >1 publications with RPA3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with RPA3 and Brain
 Blood Antibodies  >3 publications with RPA3 and Blood
 Muscle Antibodies  >2 publications with RPA3 and Muscle
 Heart Antibodies  >2 publications with RPA3 and Heart
 Lymph Antibodies  >1 publications with RPA3 and Lymph
 Skin Antibodies  >1 publications with RPA3 and Skin
 Lymph Node Antibodies  >1 publications with RPA3 and Lymph Node
 Kidney Antibodies  >1 publications with RPA3 and Kidney
 Lung Antibodies  >1 publications with RPA3 and Lung
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