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anti-ALDH1A1 antibody :: Rabbit anti-Human, Mouse Retinal dehydrogenase 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1494169
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Retinal dehydrogenase 1 (ALDH1A1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Retinal dehydrogenase 1 polyclonal Antibody(ALDH1A1)

 Product Synonym Names    RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic; ALDH1A1; ALDC; ALDH1; PUMB1
 Product Gene Name   

anti-ALDH1A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    100640
 3D Structure    ModBase 3D Structure for P00352
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Retinal dehydrogenase 1 protein(202-501aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22588 / sc-22589 / sc-50385
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ALDH1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ALDH1A1 antibody

   Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid
 Applications Tested/Suitable for anti-ALDH1A1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ALDH1A1 antibody    Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
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 Western Blot (WB) of anti-ALDH1A1 antibody    Western blot
All lanes: Retinal dehydrogenase 1 antibody at 4ug/ml+mouse liver tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 55kDa
Observed band size: 55kDa

anti-ALDH1A1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ALDH1A1 antibody    Immunohistochemistry of paraffin-embedded human small intestine using MBS1494169 at dilution 1:100
anti-ALDH1A1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ALDH1A1 antibody    Immunohistochemistry of paraffin-embedded human testicle using MBS1494169 at dilution 1:100
anti-ALDH1A1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ALDH1A1. It may not necessarily be applicable to this product.
 NCBI GI #    21361176
 NCBI GeneID    216
 NCBI Accession #    NP_000680.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000689.4 [Other Products]
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 UniProt Primary Accession #    P00352 [Other Products]
 UniProt Secondary Accession #    O00768; Q5SYR1 [Other Products]
 UniProt Related Accession #    P00352 [Other Products]
 Molecular Weight    54,862 Da
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 NCBI Official Full Name    retinal dehydrogenase 1
 NCBI Official Synonym Full Names    aldehyde dehydrogenase 1 family member A1
 NCBI Official Symbol    ALDH1A1 [Similar Products]
 NCBI Official Synonym Symbols   
ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
[Similar Products]
 NCBI Protein Information    retinal dehydrogenase 1
 UniProt Protein Name    Retinal dehydrogenase 1
 UniProt Synonym Protein Names   
ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
 Protein Family    Retinal dehydrogenase
 UniProt Gene Name    ALDH1A1 [Similar Products]
 UniProt Synonym Gene Names    ALDC; ALDH1; PUMB1; RALDH 1; RalDH1 [Similar Products]
 UniProt Entry Name    AL1A1_HUMAN
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 NCBI Summary for ALDH1A1    The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
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 UniProt Comments for ALDH1A1    ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; Apoptosis; GAPs; Oxidoreductase; GAPs, Ras; EC 1.2.1.36

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; benzaldehyde dehydrogenase (NAD+) activity; GTPase activator activity; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; ethanol oxidation; positive regulation of GTPase activity; retinol metabolic process; xenobiotic metabolic process
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 Research Articles on ALDH1A1    1. Expression of the ALDH1A1 gene is regulated by the WNT signaling pathway and co-occurs with expression of beta-catenin in prostate tumor specimens.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ALDH1A1 antibodyPathways associated with anti-ALDH1A1 antibody
 Reference Product  PubMed Publications
 ADH1B antibody  >11 publications with ALDH1A1 and ADH1B
 CYP26B1 antibody  >10 publications with ALDH1A1 and CYP26B1
 CYP26A1 antibody  >8 publications with ALDH1A1 and CYP26A1
 ADH4 antibody  >8 publications with ALDH1A1 and ADH4
 ADH1A antibody  >5 publications with ALDH1A1 and ADH1A
 ADH5 antibody  >4 publications with ALDH1A1 and ADH5
 ADH7 antibody  >3 publications with ALDH1A1 and ADH7
 CYP26C1 antibody  >2 publications with ALDH1A1 and CYP26C1
 ADH6 antibody  >2 publications with ALDH1A1 and ADH6
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Folate-Alcohol And Cancer Pathway antibodies  Folate-Alcohol And Cancer Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
Diseases associated with anti-ALDH1A1 antibodyOrgans/Tissues associated with anti-ALDH1A1 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >33 publications with ALDH1A1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >28 publications with ALDH1A1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >25 publications with ALDH1A1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >24 publications with ALDH1A1 and Nervous System Diseases
 Brain Diseases Antibodies  >23 publications with ALDH1A1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >20 publications with ALDH1A1 and Neoplasms, Experimental
 Liver Diseases Antibodies  >17 publications with ALDH1A1 and Liver Diseases
 Parkinsonian Disorders Antibodies  >14 publications with ALDH1A1 and Parkinsonian Disorders
 Liver Neoplasms Antibodies  >13 publications with ALDH1A1 and Liver Neoplasms
 Inflammation Antibodies  >11 publications with ALDH1A1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >55 publications with ALDH1A1 and Lung
 Blood Antibodies  >49 publications with ALDH1A1 and Blood
 Liver Antibodies  >48 publications with ALDH1A1 and Liver
 Brain Antibodies  >42 publications with ALDH1A1 and Brain
 Eye Antibodies  >31 publications with ALDH1A1 and Eye
 Prostate Antibodies  >16 publications with ALDH1A1 and Prostate
 Bone Antibodies  >15 publications with ALDH1A1 and Bone
 Muscle Antibodies  >15 publications with ALDH1A1 and Muscle
 Testis Antibodies  >14 publications with ALDH1A1 and Testis
 Intestine Antibodies  >14 publications with ALDH1A1 and Intestine
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