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anti-RBP4 antibody :: Rabbit anti-Human, mouse Retinol-binding protein 4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7003272
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Retinol-binding protein 4 (RBP4), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Retinol-binding protein 4 polyclonal Antibody

 Product Synonym Names    Plasma retinol-binding protein
 Product Gene Name   

anti-RBP4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    180250
 3D Structure    ModBase 3D Structure for P02753
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Retinol-binding protein 4 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27792 / sc-25850
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-RBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RBP4 antibody

   This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
 Product Categories/Family for anti-RBP4 antibody    Neuroscience
 Applications Tested/Suitable for anti-RBP4 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-RBP4 antibody    Recommended dilution: IHC: 1:20-1:200
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 Immunohistochemistry (IHC) of anti-RBP4 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS7003272 at dilution of 1:100
anti-RBP4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for RBP4. It may not necessarily be applicable to this product.
 NCBI GI #    55743122
 NCBI GeneID    5950
 NCBI Accession #    NP_006735.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006744.3 [Other Products]
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 UniProt Primary Accession #    P02753 [Other Products]
 UniProt Secondary Accession #    O43478; O43479; Q5VY24; Q8WWA3; Q9P178; D3DR38 [Other Products]
 UniProt Related Accession #    P02753 [Other Products]
 Molecular Weight    23,010 Da
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 NCBI Official Full Name    retinol-binding protein 4
 NCBI Official Synonym Full Names    retinol binding protein 4
 NCBI Official Symbol    RBP4 [Similar Products]
 NCBI Official Synonym Symbols   
RDCCAS; MCOPCB10
[Similar Products]
 NCBI Protein Information    retinol-binding protein 4
 UniProt Protein Name    Retinol-binding protein 4
 UniProt Synonym Protein Names   
Plasma retinol-binding protein; PRBP; RBP
 Protein Family    Retinol-binding protein
 UniProt Gene Name    RBP4 [Similar Products]
 UniProt Synonym Gene Names    PRBP; RBP [Similar Products]
 UniProt Entry Name    RET4_HUMAN
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 NCBI Summary for RBP4    This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RBP4    RBP4: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency). This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10q23.33

Cellular Component: cytosol; extracellular region; extracellular space; protein complex

Molecular Function: protein binding; protein heterodimerization activity; retinal binding; retinol binding

Biological Process: cardiac muscle development; embryonic organ morphogenesis; embryonic retina morphogenesis in camera-type eye; embryonic skeletal development; eye development; fat-soluble vitamin metabolic process; female genitalia morphogenesis; gluconeogenesis; glucose homeostasis; heart development; lung development; maintenance of gastrointestinal epithelium; negative regulation of cardiac muscle cell proliferation; phototransduction, visible light; positive regulation of immunoglobulin secretion; positive regulation of insulin secretion; response to ethanol; response to retinoic acid; retinoid metabolic process; retinol metabolic process; urinary bladder development; uterus development; vagina development; visual perception; vitamin metabolic process

Disease: Microphthalmia, Isolated, With Coloboma 10; Retinal Dystrophy, Iris Coloboma, And Comedogenic Acne Syndrome
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 Research Articles on RBP4    1. This review attempts to describe and summarize the variety of published mechanisms of how RBP4 can interfere with insulin signaling; these mechanisms are dissected in regard to involving retinol transport and newly-identified RBP4 membrane receptors. [Review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-RBP4 antibodyPathways associated with anti-RBP4 antibody
 Reference Product  PubMed Publications
 TTR antibody  >40 publications with RBP4 and TTR
 STRA6 antibody  >24 publications with RBP4 and STRA6
 ALB antibody  >4 publications with RBP4 and ALB
 RBP1 antibody  >4 publications with RBP4 and RBP1
 BCMO1 antibody  >2 publications with RBP4 and BCMO1
 ORM1 antibody  >1 publications with RBP4 and ORM1
 BCO2 antibody  >1 publications with RBP4 and BCO2
 RPE65 antibody  >1 publications with RBP4 and RPE65
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Diseases Of Signal Transduction Pathway antibodies  Diseases Of Signal Transduction Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Fat-soluble Vitamins Pathway antibodies  Metabolism Of Fat-soluble Vitamins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Retinoid Cycle Disease Events Pathway antibodies  Retinoid Cycle Disease Events Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Retinoid Metabolism Disease Events Pathway antibodies  Retinoid Metabolism Disease Events Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram
Diseases associated with anti-RBP4 antibodyOrgans/Tissues associated with anti-RBP4 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >100 publications with RBP4 and Inflammation
 Liver Diseases Antibodies  >75 publications with RBP4 and Liver Diseases
 Fatty Liver Antibodies  >66 publications with RBP4 and Fatty Liver
 Necrosis Antibodies  >55 publications with RBP4 and Necrosis
 Hyperglycemia Antibodies  >49 publications with RBP4 and Hyperglycemia
 Kidney Diseases Antibodies  >39 publications with RBP4 and Kidney Diseases
 Glucose Intolerance Antibodies  >36 publications with RBP4 and Glucose Intolerance
 Polycystic Ovary Syndrome Antibodies  >26 publications with RBP4 and Polycystic Ovary Syndrome
 Weight Loss Antibodies  >24 publications with RBP4 and Weight Loss
 Disease Models, Animal Antibodies  >21 publications with RBP4 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >166 publications with RBP4 and Liver
 Connective Tissue Antibodies  >120 publications with RBP4 and Connective Tissue
 Muscle Antibodies  >64 publications with RBP4 and Muscle
 Kidney Antibodies  >43 publications with RBP4 and Kidney
 Heart Antibodies  >33 publications with RBP4 and Heart
 Bone Antibodies  >18 publications with RBP4 and Bone
 Brain Antibodies  >17 publications with RBP4 and Brain
 Pancreas Antibodies  >16 publications with RBP4 and Pancreas
 Eye Antibodies  >13 publications with RBP4 and Eye
 Embryonic Tissue Antibodies  >12 publications with RBP4 and Embryonic Tissue
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