Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow RHO rightarrow Polyclonal RHO  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • MyD88 Antibody
 • AADAC siRNA
 • insulin-like growth factor 1 (somatomedin C) (IGF1) ELISA Kit
 • anti-gastric parietal cell (GPC) antibody ELISA Kit
 • Noggin Recombinant Protein
 • Mucin 5 Subtype AC (MUC5AC) ELISA Kit
 • CREB1 Antibody
 • p27-kip1 Antibody
 • Interleukin 18 (IL-18) ELISA Kit
 • Chikungunya Wild Type E1 (CHIKV) Recombinant Protein
 • Growth Hormone (gh) ELISA Kit
 • Riboflavin kinase (RFK) Recombinant Protein
 • Rho guanine nucleotide exchange factor 18 (ARHGEF18) Antibody
 • SLC5A4 - SGLT2 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-RHO antibody :: Rabbit Rhodopsin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2539162
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rhodopsin, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rhodopsin Polyclonal Antibody

 Product Synonym Names    RHO; OPN2; Rhodopsin; Opsin-2
 Product Gene Name   

anti-RHO antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 MBS2539162 Technical Datasheet    Technical Datasheet PDF
 OMIM    180380
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Affinity Purification
 Concentration    1mg/mL (lot specific)
Section Bar
 Immunogen    Synthesized peptide derived from human Rhodopsin around the non-phosphorylation site of S334.
 Calculated MW    39 kDa
 Observed MW    42 kDa
 Buffer    PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Section Bar
 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-RHO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-RHO antibody

   Retinitis pigmentosa is an inherited progressive disease which is a majorcause of blindness in western communities. It can be inherited as anautosomal dominant, autosomal recessive, or X-linked recessive disorder.In the autosomal dominant form,which comprises about 25% of totalcases, approximately 30% of families have mutations in the geneencoding the rod photoreceptor-specific protein rhodopsin. This is thetransmembrane protein which, when photoexcited, initiates the visualtransduction cascade. Defects in this gene are also one of the causes ofcongenital stationary night blindness.RHO (Rhodopsin) is a ProteinCoding gene. Diseases associated with RHO include Night Blindness,Congenital Stationary, Autosomal Dominant 1 and Retinitis Pigmentosa4, Autosomal Dominant Or Recessive. Among its related pathways are thevisual cycle I (vertebrates) and Phototransduction. GO annotations relatedto this gene include G-protein coupled receptor activity and photoreceptoractivity. An important paralog of this gene is OPN1SW
 Applications Tested/Suitable for anti-RHO antibody   

WB, IHC-p, ELISA

 Application Notes for anti-RHO antibody    WB 1:500-2000
IHC 1:100-1:300
ELISA 1:5000
Section Bar
 Western Blot (WB) of anti-RHO antibody    Western Blot analysis of COLO205 cells with Rhodopsin Polyclonal Antibody.
anti-RHO antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RHO. It may not necessarily be applicable to this product.
 NCBI GI #    4506527
 NCBI GeneID    6010
 NCBI Accession #    NP_000530.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000539.3 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q16414; Q2M249 [Other Products]
 UniProt Related Accession #    P08100 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    rhodopsin
 NCBI Official Synonym Full Names    rhodopsin
 NCBI Official Symbol    RHO [Similar Products]
 NCBI Official Synonym Symbols   
RP4; OPN2; CSNBAD1
[Similar Products]
 NCBI Protein Information    rhodopsin
 UniProt Protein Name    Rhodopsin
 UniProt Synonym Protein Names   
Opsin-2
 Protein Family    Rhodopsin
 UniProt Gene Name    RHO [Similar Products]
 UniProt Synonym Gene Names    OPN2 [Similar Products]
 UniProt Entry Name    OPSD_HUMAN
Section Bar
 NCBI Summary for RHO    Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for RHO    Rhodopsin: a G-protein coupled receptor. The light-absorbing visual pigment in Rod photoreceptor cells. Mediates vision in dim light. Consists of the apoprotein, opsin, covalently linked to cis-retinal. Defects in RHO are a cause of autosomal retinitis pigmentosa and congenital stationary night blindness.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3q21-q24

Cellular Component: Golgi apparatus; Golgi membrane; integral to plasma membrane; intercellular junction; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; rough endoplasmic reticulum membrane

Molecular Function: G-protein coupled receptor activity; metal ion binding; photoreceptor activity; protein binding; retinal binding

Biological Process: absorption of visible light; G-protein coupled receptor protein signaling pathway; organelle organization and biogenesis; photoreceptor cell maintenance; phototransduction, visible light; protein amino acid phosphorylation; protein-chromophore linkage; red, far-red light phototransduction; regulation of rhodopsin mediated signaling; retina development in camera-type eye; retinoid metabolic process; rhodopsin mediated signaling; visual perception

Disease: Fundus Albipunctatus; Night Blindness, Congenital Stationary, Autosomal Dominant 1; Retinitis Pigmentosa 4
Table BarTOPTable Bar
 Research Articles on RHO    1. Similar vacuolization in photoreceptor outer segment discs of transgenic mice expressing human rhodopsin with a T17M mutation or non-glycosylated form of rhodopsin was found. Non-glycosylated rhodopsin is unstable and is regulated via ubiquitin pathway
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-RHO antibodyPathways associated with anti-RHO antibody
 Reference Product  PubMed Publications
 GRK1 antibody  >17 publications with RHO and GRK1
 GNAT1 antibody  >13 publications with RHO and GNAT1
 SAG antibody  >8 publications with RHO and SAG
 RCVRN antibody  >3 publications with RHO and RCVRN
 RLBP1 antibody  >2 publications with RHO and RLBP1
 GNAT2 antibody  >2 publications with RHO and GNAT2
 GRK7 antibody  >1 publications with RHO and GRK7
 GNGT1 antibody  >1 publications with RHO and GNGT1
 Products by Pathway  Pathway Diagram
 Activation Of The Phototransduction Cascade Pathway antibodies  Activation Of The Phototransduction Cascade Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies  Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with anti-RHO antibodyOrgans/Tissues associated with anti-RHO antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1521 publications with RHO and Inflammation
 Lung Diseases Antibodies  >1269 publications with RHO and Lung Diseases
 Heart Diseases Antibodies  >1176 publications with RHO and Heart Diseases
 Autoimmune Diseases Antibodies  >755 publications with RHO and Autoimmune Diseases
 Necrosis Antibodies  >730 publications with RHO and Necrosis
 Liver Diseases Antibodies  >656 publications with RHO and Liver Diseases
 Fibrosis Antibodies  >643 publications with RHO and Fibrosis
 Kidney Diseases Antibodies  >567 publications with RHO and Kidney Diseases
 Hemorrhage Antibodies  >530 publications with RHO and Hemorrhage
 Cell Transformation, Neoplastic Antibodies  >422 publications with RHO and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3447 publications with RHO and Muscle
 Brain Antibodies  >2916 publications with RHO and Brain
 Eye Antibodies  >1298 publications with RHO and Eye
 Uncharacterized Tissue Antibodies  >10 publications with RHO and Uncharacterized Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions