CAA41107.1
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
Molecular Weight
Calculated MW: 11 Observed MW: 10
NCBI Official Full Name
S100 alpha protein
UniProt Protein Name
Protein S100-A1
UniProt Synonym Protein Names
S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1
UniProt Synonym Gene Names
UniProt Entry Name
S10A1_HUMAN
UniProt Comments for S-100 alpha
S100A1: Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Interacts with AGER and CAPZA1. Interacts with FKBP4. Interacts with RYR1 and RYR2. Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. Belongs to the S-100 family.
Protein type: Calcium-binding; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: M band; neuron projection; nucleus; protein complex; sarcoplasmic reticulum; Z disc
Molecular Function: ATPase binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding; protein homodimerization activity
Biological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of heart contraction; substantia nigra development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-S-100 alpha antibody
Diseases associated with anti-S-100 alpha antibody
Organs/Tissues associated with anti-S-100 alpha antibody
|